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Gender-Affirming Treatment and Employment Rate in 3812 Danish Transgender Persons and 38 120 Controls

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Název: Gender-Affirming Treatment and Employment Rate in 3812 Danish Transgender Persons and 38 120 Controls
Autoři: Dorte Glintborg, Jens-Jakob Kjer Møller, Katrine Hass Rubin, Øjvind Lidegaard, Guy T’Sjoen, Mie-Louise Julie Ørsted Larsen, Malene Hilden, Marianne Skovsager Andersen
Zdroj: The Journal of Clinical Endocrinology & Metabolism. 109:3076-3086
Informace o vydavateli: The Endocrine Society, 2024.
Rok vydání: 2024
Témata: Male, Adult, Employment, Adolescent, Denmark, Transgender Persons, socioeconomic status, Cohort Studies, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Transgender Persons/statistics & numerical data, Humans, register-based, Registries, Gender Dysphoria, Employment/statistics & numerical data, Sex Reassignment Procedures/statistics & numerical data, Registries/statistics & numerical data, Gender Dysphoria/epidemiology, transgender, Denmark/epidemiology, Case-Control Studies, medicine prescription, Female, Gender-Affirming Procedures, gender-affirming hormone, mental health
Popis: Objective Gender-affirming care could be associated with higher employment rate. We assessed employment rates in transgender persons compared to controls and demographic, health, and treatment-related factors associated with employment in transgender persons. Methods National register-based cohort study in Danish persons with diagnosis code of gender dysphoria during year 2000-2021. Five age-matched controls of the same sex at birth and 5 age-matched controls of the other sex at birth were included. The date of study inclusion was the first date of transgender diagnosis. Employment was the primary study outcome. Results The cohort included 3812 transgender persons and 38 120 cisgender controls. The median age (interquartile range) was 19 (15; 24) years for transgender men, n = 1993 and 23 (19; 33) years for transgender women, n = 1819. In transgender men compared to control cisgender women, the odds ratio (OR) (95% CI) for employment was 0.33 (0.29; 0.38) before study inclusion and 0.24 (0.20; 0.29) in the fifth calendar year after index; in transgender women compared to control cisgender men, corresponding ORs were 0.30 (0.70; 0.34) and 0.21 (0.18; 0.25). Similar findings were observed between transgender persons and cisgender controls of other sex. Use of gender-affirming hormone in transgender men increased probability of employment at all time points after 5 years (OR 1.61 [95% CI: 1.08; 2.42], P = .02). In transgender women, use of hormone treatment was not associated with changed employment rates at 5 years (OR 1.31 [0.94; 1.82], P = .11). Conclusion Masculinizing hormone treatment was associated with higher probability of employment.
Druh dokumentu: Article
Jazyk: English
ISSN: 1945-7197
0021-972X
DOI: 10.1210/clinem/dgae351
Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38771642
https://portal.findresearcher.sdu.dk/da/publications/ac50fa9c-26d9-497f-be3e-34048c875a77
https://doi.org/10.1210/clinem/dgae351
Rights: OUP Standard Publication Reuse
Přístupové číslo: edsair.doi.dedup.....29c08a5d59b7e914f8647449b9674f7d
Databáze: OpenAIRE
Popis
Abstrakt:Objective Gender-affirming care could be associated with higher employment rate. We assessed employment rates in transgender persons compared to controls and demographic, health, and treatment-related factors associated with employment in transgender persons. Methods National register-based cohort study in Danish persons with diagnosis code of gender dysphoria during year 2000-2021. Five age-matched controls of the same sex at birth and 5 age-matched controls of the other sex at birth were included. The date of study inclusion was the first date of transgender diagnosis. Employment was the primary study outcome. Results The cohort included 3812 transgender persons and 38 120 cisgender controls. The median age (interquartile range) was 19 (15; 24) years for transgender men, n = 1993 and 23 (19; 33) years for transgender women, n = 1819. In transgender men compared to control cisgender women, the odds ratio (OR) (95% CI) for employment was 0.33 (0.29; 0.38) before study inclusion and 0.24 (0.20; 0.29) in the fifth calendar year after index; in transgender women compared to control cisgender men, corresponding ORs were 0.30 (0.70; 0.34) and 0.21 (0.18; 0.25). Similar findings were observed between transgender persons and cisgender controls of other sex. Use of gender-affirming hormone in transgender men increased probability of employment at all time points after 5 years (OR 1.61 [95% CI: 1.08; 2.42], P = .02). In transgender women, use of hormone treatment was not associated with changed employment rates at 5 years (OR 1.31 [0.94; 1.82], P = .11). Conclusion Masculinizing hormone treatment was associated with higher probability of employment.
ISSN:19457197
0021972X
DOI:10.1210/clinem/dgae351