Wilson’s Disease with Lymphoproliferative Disorder: A Case Report
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| Title: | Wilson’s Disease with Lymphoproliferative Disorder: A Case Report |
|---|---|
| Authors: | Ashish Jha, Saroj Kumar Sah, Ravi Ranjan Pradhan |
| Source: | Journal of Nepal Medical Association, Vol 63, Iss 285 (2025) |
| Publisher Information: | Journal of Nepal Medical Association (JNMA), 2025. |
| Publication Year: | 2025 |
| Subject Terms: | Medicine (General), R5-920, hematological disorder, Wilson's disease, neurological manifestation |
| Description: | Wilson's disease is characterized by copper accumulation in organs like liver, brain, and eyes, presenting with a varied clinical features, making it challenging to diagnose. This report describes a case of Wilson’s disease with unusual hematological features. A 12-year-old from Himalayan region presented with weakness, dysarthria, tremors. Initial investigations revealed pancytopenia, and bone marrow showed a lymphoproliferative disorder. He developed behavioral changes, a flat affect, and scanning speech. Wilson’s disease was confirmed through Kayser-Fleischer rings, reduced serum ceruloplasmin levels, and elevated urinary copper, supported by imaging. |
| Document Type: | Article |
| ISSN: | 1815-672X 0028-2715 |
| DOI: | 10.31729/jnma.8983 |
| Access URL: | https://doaj.org/article/f3347d5af5334c3e9d92e7361acc5d1c |
| Rights: | CC BY |
| Accession Number: | edsair.doi.dedup.....24a9d2c4110ba88b5437bbb0921b4c8b |
| Database: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstract: | Wilson's disease is characterized by copper accumulation in organs like liver, brain, and eyes, presenting with a varied clinical features, making it challenging to diagnose. This report describes a case of Wilson’s disease with unusual hematological features. A 12-year-old from Himalayan region presented with weakness, dysarthria, tremors. Initial investigations revealed pancytopenia, and bone marrow showed a lymphoproliferative disorder. He developed behavioral changes, a flat affect, and scanning speech. Wilson’s disease was confirmed through Kayser-Fleischer rings, reduced serum ceruloplasmin levels, and elevated urinary copper, supported by imaging. |
|---|---|
| ISSN: | 1815672X 00282715 |
| DOI: | 10.31729/jnma.8983 |