Relation between perinatal outcome and gestational duration in term primiparous pregnancies stratified by body mass index
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| Titel: | Relation between perinatal outcome and gestational duration in term primiparous pregnancies stratified by body mass index |
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| Autoren: | Lina Lindegren, Andrea Stuart, Andreas Herbst, Karin Källén |
| Quelle: | Acta Obstet Gynecol Scand Acta Obstetricia et Gynecologica Scandinavica, Vol 101, Iss 12, Pp 1414-1421 (2022) |
| Verlagsinformationen: | Wiley, 2022. |
| Publikationsjahr: | 2022 |
| Schlagwörter: | obesity, body mass index, Gestational Age, Body Mass Index, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Risk Factors, overweight, Humans, Apgar score, Obesity, Child, 2. Zero hunger, Infant, Newborn, Pregnancy Outcome, Infant, gestational duration, Gynecology and obstetrics, Stillbirth, 3. Good health, perinatal outcome, RG1-991, Apgar Score, Female |
| Beschreibung: | IntroductionThere is growing evidence that induction of labor at 41 completed weeks improves neonatal outcome, at least among primiparous women. This study was performed to investigate whether maternal body mass index (BMI) should be considered when deciding on timing of intervention in term pregnancies.Material and methodsThe study design was a historical cohort study using data from the Swedish Medical Birth Register, singletons in cephalic presentation with births 39+0 to 41+6 weeks, with available information on maternal BMI 2005–2017 (n = 352 567). Modified Poisson regression analyses were used to investigate the association between gestational duration and stillbirth or death before 45 postmenstrual weeks (primary outcome) and Apgar score ResultsThe adjusted relative risk (ARR) of stillbirth or death before 45 weeks among infants born at 41+0 to 41+6 vs 40+0 to 40+6 weeks, was 1.26 with a 95% confidence interval (CI) of 1.07–1.48. Among women with BMI ≥30, the offspring mortality risk in pregnancies lasting 39+0 to 39+2 weeks was significantly above the corresponding risk among women of normal BMI who delivered at 41+0 to 41+2 weeks (ARR = 1.95; 95% CI 1.07–3.56) but no statistically significant heterogeneity was found regarding the magnitude of the association between gestational duration and offspring mortality. The ARR, for Apgar ConclusionsIn primiparous women with obesity the risk of stillbirth or death before 45 postmenstrual weeks were increased throughout all full‐term gestational age categories, compared with women with overweight or normal BMI. Children to obese women had the same risk for Apgar scores |
| Publikationsart: | Article Other literature type |
| Sprache: | English |
| ISSN: | 1600-0412 0001-6349 |
| DOI: | 10.1111/aogs.14465 |
| Zugangs-URL: | https://pubmed.ncbi.nlm.nih.gov/36168197 https://doaj.org/article/0ca5f7e68d2d40ca8cb44853697213fd |
| Rights: | CC BY NC |
| Dokumentencode: | edsair.doi.dedup.....22cddfc6fa3f15109f1d8a4a4aedaa60 |
| Datenbank: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstract: | IntroductionThere is growing evidence that induction of labor at 41 completed weeks improves neonatal outcome, at least among primiparous women. This study was performed to investigate whether maternal body mass index (BMI) should be considered when deciding on timing of intervention in term pregnancies.Material and methodsThe study design was a historical cohort study using data from the Swedish Medical Birth Register, singletons in cephalic presentation with births 39+0 to 41+6 weeks, with available information on maternal BMI 2005–2017 (n = 352 567). Modified Poisson regression analyses were used to investigate the association between gestational duration and stillbirth or death before 45 postmenstrual weeks (primary outcome) and Apgar score ResultsThe adjusted relative risk (ARR) of stillbirth or death before 45 weeks among infants born at 41+0 to 41+6 vs 40+0 to 40+6 weeks, was 1.26 with a 95% confidence interval (CI) of 1.07–1.48. Among women with BMI ≥30, the offspring mortality risk in pregnancies lasting 39+0 to 39+2 weeks was significantly above the corresponding risk among women of normal BMI who delivered at 41+0 to 41+2 weeks (ARR = 1.95; 95% CI 1.07–3.56) but no statistically significant heterogeneity was found regarding the magnitude of the association between gestational duration and offspring mortality. The ARR, for Apgar ConclusionsIn primiparous women with obesity the risk of stillbirth or death before 45 postmenstrual weeks were increased throughout all full‐term gestational age categories, compared with women with overweight or normal BMI. Children to obese women had the same risk for Apgar scores |
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| ISSN: | 16000412 00016349 |
| DOI: | 10.1111/aogs.14465 |