Impact of diabetes mellitus on postoperative complications in patients undergoing pancreatic surgery
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| Název: | Impact of diabetes mellitus on postoperative complications in patients undergoing pancreatic surgery |
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| Autoři: | Sandra de Kalbermatten, David Martin, Emilie Uldry, Emmanuel Melloul, Nicolas Demartines, David Fuks, Gaëtan-Romain Joliat |
| Zdroj: | HPB, vol. 27, no. 4, pp. 530-537 |
| Informace o vydavateli: | Elsevier BV, 2025. |
| Rok vydání: | 2025 |
| Témata: | Male, Middle Aged, Risk Assessment, Body Mass Index, Biliary Tract Surgical Procedures, Cross-Sectional Studies, Pancreatectomy, Postoperative Complications, Predictive Value of Tests, Enhanced Recovery After Surgery, Pancreatectomy/adverse effects, Pancreatectomy/rehabilitation, Pancreatectomy/statistics & numerical data, Morbidity, Patient Compliance/statistics & numerical data, Diabetes Mellitus/epidemiology, Diabetes Mellitus/surgery, Postoperative Complications/epidemiology, Postoperative Complications/etiology, Postoperative Complications/prevention & control, Biliary Tract Surgical Procedures/adverse effects, Biliary Tract Surgical Procedures/statistics & numerical data, Stents/adverse effects, Stents/statistics & numerical data, Risk Assessment/methods, Risk Assessment/statistics & numerical data, Retrospective Studies, Humans, Female, Aged, Diabetes Mellitus, Patient Compliance, Stents |
| Popis: | Enhanced Recovery After Surgery (ERAS) protocols decrease postoperative complications, but data on their effect on diabetic patients undergoing pancreatectomy are scarce. This study assessed whether diabetes mellitus (DM) was a morbidity predictor after pancreatectomy within an ERAS program.A cross-sectional study including all patients who underwent pancreatectomy (2012-2022) and followed an ERAS pathway was performed. Multivariable analysis was used to determine whether DM was a morbidity predictor. Association between ERAS compliance and morbidity rate was assessed.A total of 558 patients were included (266 women, median age 66, median body-mass index 25). Most patients underwent open pancreatoduodenectomy (n=369, 66%). In diabetic patients with overall ERAS compliance≤60 %, morbidity was 38/40 (95%), whereas in diabetic patients with overall ERAS compliance>60 %, it decreased to 37/50 (74%, p=0.008). DM was not found as an independent complication predictor (OR 0.7, 95%CI 0.4-1.2, p=0.186), while body-mass index>25 kg/m2 and preoperative biliary stenting were preoperative morbidity predictors (OR 1.1, 95%CI 1.0-1.1, p=0.049; OR 1.7, 95%CI 1.0-2.5, p=0.044).This study showed that DM was not associated with postoperative complications after pancreatectomy within an ERAS program. It highlighted the importance of a good ERAS compliance to decrease the risk of postoperative complications in DM patients. |
| Druh dokumentu: | Article |
| Popis souboru: | application/pdf |
| Jazyk: | English |
| ISSN: | 1365-182X |
| DOI: | 10.1016/j.hpb.2024.12.020 |
| Přístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/39799092 https://serval.unil.ch/notice/serval:BIB_0F51C2790E9D https://serval.unil.ch/resource/serval:BIB_0F51C2790E9D.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_0F51C2790E9D0 |
| Rights: | CC BY |
| Přístupové číslo: | edsair.doi.dedup.....1ea69fcb647e017a2fc8e2eb99e3348c |
| Databáze: | OpenAIRE |
Nájsť tento článok vo Web of Science | Abstrakt: | Enhanced Recovery After Surgery (ERAS) protocols decrease postoperative complications, but data on their effect on diabetic patients undergoing pancreatectomy are scarce. This study assessed whether diabetes mellitus (DM) was a morbidity predictor after pancreatectomy within an ERAS program.A cross-sectional study including all patients who underwent pancreatectomy (2012-2022) and followed an ERAS pathway was performed. Multivariable analysis was used to determine whether DM was a morbidity predictor. Association between ERAS compliance and morbidity rate was assessed.A total of 558 patients were included (266 women, median age 66, median body-mass index 25). Most patients underwent open pancreatoduodenectomy (n=369, 66%). In diabetic patients with overall ERAS compliance≤60 %, morbidity was 38/40 (95%), whereas in diabetic patients with overall ERAS compliance>60 %, it decreased to 37/50 (74%, p=0.008). DM was not found as an independent complication predictor (OR 0.7, 95%CI 0.4-1.2, p=0.186), while body-mass index>25 kg/m2 and preoperative biliary stenting were preoperative morbidity predictors (OR 1.1, 95%CI 1.0-1.1, p=0.049; OR 1.7, 95%CI 1.0-2.5, p=0.044).This study showed that DM was not associated with postoperative complications after pancreatectomy within an ERAS program. It highlighted the importance of a good ERAS compliance to decrease the risk of postoperative complications in DM patients. |
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| ISSN: | 1365182X |
| DOI: | 10.1016/j.hpb.2024.12.020 |