Evolutionary paths to mammalian longevity through the lens of gene expression
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| Název: | Evolutionary paths to mammalian longevity through the lens of gene expression |
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| Autoři: | Ulaş Işıldak, Handan Melike Dönertaş |
| Zdroj: | EMBO J |
| Informace o vydavateli: | Springer Science and Business Media LLC, 2023. |
| Rok vydání: | 2023 |
| Témata: | Mammals, 0301 basic medicine, Aging, 0303 health sciences, 03 medical and health sciences, Methionine, Longevity, Animals, Gene Expression, News & Views, Methionine/genetics, Aging/genetics [MeSH], Longevity/genetics [MeSH], Aging/metabolism [MeSH], Methionine/genetics [MeSH], Gene Expression [MeSH], Animals [MeSH], Aging/metabolism, Aging/genetics, Methionine/metabolism, Longevity/genetics, Methionine/metabolism [MeSH], Mammals/genetics, Mammals/genetics [MeSH] |
| Popis: | The natural variation in mammalian longevity and its underlying mechanisms remain an active area of aging research. In the latest issue of The EMBO Journal, Liu et al (2023) analyze gene expression levels in 103 mammalian species across three tissues, revealing tissue‐specific associations between gene expression patterns and longevity. Remarkably, the study suggests that methionine restriction, a strategy shown to increase lifespan, may extend beyond artificial interventions and is similarly employed by natural selection. |
| Druh dokumentu: | Article Other literature type |
| Jazyk: | English |
| ISSN: | 1460-2075 0261-4189 |
| DOI: | 10.15252/embj.2023114879 |
| Přístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/37519235 https://repository.publisso.de/resource/frl:6475550 |
| Rights: | CC BY |
| Přístupové číslo: | edsair.doi.dedup.....1b52d2789765a9e0f30b5fa53c742979 |
| Databáze: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstrakt: | The natural variation in mammalian longevity and its underlying mechanisms remain an active area of aging research. In the latest issue of The EMBO Journal, Liu et al (2023) analyze gene expression levels in 103 mammalian species across three tissues, revealing tissue‐specific associations between gene expression patterns and longevity. Remarkably, the study suggests that methionine restriction, a strategy shown to increase lifespan, may extend beyond artificial interventions and is similarly employed by natural selection. |
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| ISSN: | 14602075 02614189 |
| DOI: | 10.15252/embj.2023114879 |