Preparation and Formulation of Adulsa Cough Syrup
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| Title: | Preparation and Formulation of Adulsa Cough Syrup |
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| Authors: | Hanuman Idhole*, Swati Aswani, Dr M.D. Kitukale |
| Publisher Information: | International Journal of Pharmaceutical Sciences, 2025. |
| Publication Year: | 2025 |
| Subject Terms: | Herbal syrup, Adulsa, Tulsi, Ginger, Licorice, Cough remedy, Antitussive, Expectorant, Polyherbal formulation, Natural medicine, Phytotherapy, Respiratory health, Mucolytic, Ayurvedic medicine, Stability testing |
| Description: | The present study aims to develop a safe, effective, and palatable polyherbal cough syrup utilizing traditional medicinal herbs. The formulation incorporates Adulsa (Justicia adhatoda), Tulsi (Ocimum sanctum), Ginger (Zingiber officinale), and Licorice (Glycyrrhiza glabra)—herbs known for their antitussive, expectorant, anti-inflammatory, antimicrobial, and soothing properties. The syrup was prepared using aqueous and hydroalcoholic extractions, combined with honey, sugar syrup, citric acid, sodium benzoate, and natural flavors, and evaluated for its physicochemical and microbiological properties. The final herbal syrup exhibited ideal organoleptic characteristics, including a clear brown appearance, sweet herbal taste, and smooth viscous texture. The physicochemical evaluations showed a pH of 5.1, viscosity of 1200 cP, specific gravity of 1.24, and a refractive index of 1.439. Microbial testing confirmed the absence of pathogenic organisms such as E. coli and Salmonella, with total microbial counts well within acceptable limits. The syrup maintained its stability over 3 months under accelerated storage conditions. This formulation demonstrated promising expectorant and mucolytic activity with high patient compliance, making it a potential natural alternative to conventional synthetic cough syrups. The study supports the use of traditional herbal ingredients, validated by modern scientific methods, to address respiratory conditions effectively and safely. |
| Document Type: | Article |
| DOI: | 10.5281/zenodo.15640478 |
| DOI: | 10.5281/zenodo.15640479 |
| Rights: | CC BY |
| Accession Number: | edsair.doi.dedup.....17f3f92430f7c4c217fdc422a39a6604 |
| Database: | OpenAIRE |
Nájsť tento článok vo Web of Science | Abstract: | The present study aims to develop a safe, effective, and palatable polyherbal cough syrup utilizing traditional medicinal herbs. The formulation incorporates Adulsa (Justicia adhatoda), Tulsi (Ocimum sanctum), Ginger (Zingiber officinale), and Licorice (Glycyrrhiza glabra)—herbs known for their antitussive, expectorant, anti-inflammatory, antimicrobial, and soothing properties. The syrup was prepared using aqueous and hydroalcoholic extractions, combined with honey, sugar syrup, citric acid, sodium benzoate, and natural flavors, and evaluated for its physicochemical and microbiological properties. The final herbal syrup exhibited ideal organoleptic characteristics, including a clear brown appearance, sweet herbal taste, and smooth viscous texture. The physicochemical evaluations showed a pH of 5.1, viscosity of 1200 cP, specific gravity of 1.24, and a refractive index of 1.439. Microbial testing confirmed the absence of pathogenic organisms such as E. coli and Salmonella, with total microbial counts well within acceptable limits. The syrup maintained its stability over 3 months under accelerated storage conditions. This formulation demonstrated promising expectorant and mucolytic activity with high patient compliance, making it a potential natural alternative to conventional synthetic cough syrups. The study supports the use of traditional herbal ingredients, validated by modern scientific methods, to address respiratory conditions effectively and safely. |
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| DOI: | 10.5281/zenodo.15640478 |