Prenatal Exposure to Nitrate in Drinking Water and Adverse Health Outcomes in the Offspring: a Review of Current Epidemiological Research

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Názov: Prenatal Exposure to Nitrate in Drinking Water and Adverse Health Outcomes in the Offspring: a Review of Current Epidemiological Research
Autori: Pernille Jul Clemmensen, Jörg Schullehner, Nis Brix, Torben Sigsgaard, Leslie Thomas Stayner, Henrik Albert Kolstad, Cecilia Høst Ramlau-Hansen
Zdroj: Curr Environ Health Rep
Clemmensen, P J, Schullehner, J, Brix, N, Sigsgaard, T, Stayner, L T, Kolstad, H A & Ramlau-Hansen, C H 2023, 'Prenatal Exposure to Nitrate in Drinking Water and Adverse Health Outcomes in the Offspring : a Review of Current Epidemiological Research', Current Environmental Health Reports, vol. 10, no. 3, pp. 250-263. https://doi.org/10.1007/s40572-023-00404-9
Current Environmental Health Reports
Informácie o vydavateľovi: Springer Science and Business Media LLC, 2023.
Rok vydania: 2023
Predmety: Adult, Nitrates, Drinking Water/adverse effects, Drinking Water, Prenatal Exposure Delayed Effects/chemically induced, Infant, Newborn, Nitrates/adverse effects, Nitrate, 6. Clean water, Article, 3. Good health, Young Adult, Epidemiologic Studies, Pregnancy, Prenatal Exposure Delayed Effects, Outcome Assessment, Health Care, Drinking water, Prenatal, Humans, Female
Popis: Purpose of ReviewRecently, several epidemiological studies have investigated whether prenatal exposure to nitrate from drinking water may be harmful to the fetus, even at nitrate levels below the current World Health Organization drinking water standard. The purpose of this review was to give an overview of the newest knowledge on potential health effects of prenatal exposure to nitrate.Recent FindingsWe included 13 epidemiological studies conducted since 2017. Nine studies investigated outcomes appearing around birth, and four studies investigated health outcomes appearing in childhood and young adulthood.SummaryThe reviewed studies showed some indications of higher risk of preterm delivery, lower birth weight, birth defects, and childhood cancer related to prenatal exposure to nitrate. However, the numbers of studies for each outcome were sparse, and some of the results were conflicting. We suggest that there is a need for additional studies and particularly for studies that include information on water consumption patterns, intake of nitrate from diet, and intake of nitrosatable drugs.
Druh dokumentu: Article
Other literature type
Popis súboru: application/pdf
Jazyk: English
ISSN: 2196-5412
DOI: 10.1007/s40572-023-00404-9
Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37453984
https://pure.au.dk/ws/files/404086968/Prenatal_Exposure_to_Nitrate_in_Drinking_Water_and_Adverse_Health_Outcomes_in_the_Offspring_a_Review_of_Current_Epidemiological_Research.pdf
Rights: CC BY
Prístupové číslo: edsair.doi.dedup.....16a94e164bffaad0f14c4f805945b81d
Databáza: OpenAIRE
Popis
Abstrakt:Purpose of ReviewRecently, several epidemiological studies have investigated whether prenatal exposure to nitrate from drinking water may be harmful to the fetus, even at nitrate levels below the current World Health Organization drinking water standard. The purpose of this review was to give an overview of the newest knowledge on potential health effects of prenatal exposure to nitrate.Recent FindingsWe included 13 epidemiological studies conducted since 2017. Nine studies investigated outcomes appearing around birth, and four studies investigated health outcomes appearing in childhood and young adulthood.SummaryThe reviewed studies showed some indications of higher risk of preterm delivery, lower birth weight, birth defects, and childhood cancer related to prenatal exposure to nitrate. However, the numbers of studies for each outcome were sparse, and some of the results were conflicting. We suggest that there is a need for additional studies and particularly for studies that include information on water consumption patterns, intake of nitrate from diet, and intake of nitrosatable drugs.
ISSN:21965412
DOI:10.1007/s40572-023-00404-9