Nature's laboratory: plant metabolic engineering methods using phenylpropanoids as a case study
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| Název: | Nature's laboratory: plant metabolic engineering methods using phenylpropanoids as a case study |
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| Autoři: | Caroline Van Beirs, Ilias El Houari, Bartel Vanholme |
| Zdroj: | Biotechnol Biofuels Bioprod BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS |
| Informace o vydavateli: | Springer Science and Business Media LLC, 2025. |
| Rok vydání: | 2025 |
| Témata: | ROOT CULTURES, CELL-SUSPENSION CULTURES, ENZYME, TRANSPORTER, Biology and Life Sciences, Review, Plants, ARABIDOPSIS, BIOSYNTHETIC-PATHWAY, Specialised metabolites, PHENYLALANINE AMMONIA-LYASE, ACID, Phenylpropanoids, SHIKIMATE PATHWAY, OVEREXPRESSION, Metabolic engineering |
| Popis: | Plant specialised metabolism generates a vast array of compounds with significant potential across agriculture, medicine, cosmetics, and the food industry. A key challenge lies in optimising their production in the plant, as these compounds are often present in trace amounts in a complex metabolic cocktail. Given their high economic value, extensive efforts have been made to elucidate their biosynthetic pathways and pinpoint key regulatory and enzymatic targets. This knowledge has been applied for metabolic engineering to enhance the carbon flux towards metabolites of interest, thereby broadening the utility of plants as a source of high-value compounds. This review examines different metabolic engineering strategies employed today using the phenylpropanoid pathway as a case study and highlights the potential of integrating plant and microbial research to drive cross-disciplinary innovation. |
| Druh dokumentu: | Article Other literature type |
| Popis souboru: | application/pdf |
| Jazyk: | English |
| ISSN: | 2731-3654 |
| DOI: | 10.1186/s13068-025-02684-9 |
| Přístupová URL adresa: | https://biblio.ugent.be/publication/01K18V86ZG6JVTWNKGPBYG30G5 https://biblio.ugent.be/publication/01K18V86ZG6JVTWNKGPBYG30G5/file/01K35VGC2MJYFSTSQVXXR94EAZ http://hdl.handle.net/1854/LU-01K18V86ZG6JVTWNKGPBYG30G5 http://doi.org/10.1186/s13068-025-02684-9 |
| Rights: | CC BY |
| Přístupové číslo: | edsair.doi.dedup.....169c0376bb44663b8db7b83c304f0f9b |
| Databáze: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstrakt: | Plant specialised metabolism generates a vast array of compounds with significant potential across agriculture, medicine, cosmetics, and the food industry. A key challenge lies in optimising their production in the plant, as these compounds are often present in trace amounts in a complex metabolic cocktail. Given their high economic value, extensive efforts have been made to elucidate their biosynthetic pathways and pinpoint key regulatory and enzymatic targets. This knowledge has been applied for metabolic engineering to enhance the carbon flux towards metabolites of interest, thereby broadening the utility of plants as a source of high-value compounds. This review examines different metabolic engineering strategies employed today using the phenylpropanoid pathway as a case study and highlights the potential of integrating plant and microbial research to drive cross-disciplinary innovation. |
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| ISSN: | 27313654 |
| DOI: | 10.1186/s13068-025-02684-9 |