Variations in end-of-life practices in intensive care units worldwide (Ethicus-2): a prospective observational study
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| Názov: | Variations in end-of-life practices in intensive care units worldwide (Ethicus-2): a prospective observational study |
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| Autori: | Avidan, Alexander, Sprung, Charles, Schefold, Joerg, Ricou, Bara, Hartog, Christiane, Nates, Joseph, Jaschinski, Ulrich, Lobo, Suzana, Joynt, Gavin, Lesieur, Olivier, Weiss, Manfred, Antonelli, Massimo, Bülow, Hans-Henrik, Bocci, Maria, Robertsen, Annette, Anstey, Matthew, Estébanez-Montiel, Belén, Lautrette, Alexandre, Gruber, Anastasiia, Estella, Angel, Mullick, Sudakshina, Sreedharan, Roshni, Michalsen, Andrej, Feldman, Charles, Tisljar, Kai, Posch, Martin, Ovu, Steven, Tamowicz, Barbara, Demoule, Alexandre, Dekeyser Ganz, Freda, Pargger, Hans, Noto, Alberto, Metnitz, Philipp, Zubek, Laszlo, de la Guardia, Veronica, Danbury, Christopher, Szűcs, Orsolya, Protti, Alessandro, Filipe, Mario, Simpson, Steven, Green, Cameron, Giannini, Alberto, Soliman, Ivo, Piras, Claudio, Caser, Eliana, Hache-Marliere, Manuel, Mentzelopoulos, Spyros |
| Prispievatelia: | Demoule, Alexandre |
| Zdroj: | The Lancet Respiratory Medicine. 9:1101-1110 |
| Informácie o vydavateľovi: | Elsevier BV, 2021. |
| Rok vydania: | 2021 |
| Predmety: | Adult, Terminal Care, Decision Making, 3. Good health, 12. Responsible consumption, [SDV] Life Sciences [q-bio], Death, Life Support Care, Intensive Care Units, 03 medical and health sciences, 0302 clinical medicine, N/A, Humans, Prospective Studies, Sustaining Treatments, ICU Patienties, Withdrawal, Decisions, Resuscitation, Guidelines, Illness, Support, Orders |
| Popis: | End-of-life practices vary among intensive care units (ICUs) worldwide. Differences can result in variable use of disproportionate or non-beneficial life-sustaining interventions across diverse world regions. This study investigated global disparities in end-of-life practices.In this prospective, multinational, observational study, consecutive adult ICU patients who died or had a limitation of life-sustaining treatment (withholding or withdrawing life-sustaining therapy and active shortening of the dying process) during a 6-month period between Sept 1, 2015, and Sept 30, 2016, were recruited from 199 ICUs in 36 countries. The primary outcome was the end-of-life practice as defined by the end-of-life categories: withholding or withdrawing life-sustaining therapy, active shortening of the dying process, or failed cardiopulmonary resuscitation (CPR). Patients with brain death were included in a separate predefined end-of-life category. Data collection included patient characteristics, diagnoses, end-of-life decisions and their timing related to admission and discharge, or death, with comparisons across different regions. Patients were studied until death or 2 months from the first limitation decision.Of 87 951 patients admitted to ICU, 12 850 (14·6%) were included in the study population. The number of patients categorised into each of the different end-of-life categories were significantly different for each region (p |
| Druh dokumentu: | Article |
| Popis súboru: | application/pdf |
| Jazyk: | English |
| ISSN: | 2213-2600 |
| DOI: | 10.1016/s2213-2600(21)00261-7 |
| DOI: | 10.48350/158351 |
| Prístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/34364537 https://hal.science/hal-03995024v1 https://doi.org/10.1016/s2213-2600(21)00261-7 https://europepmc.org/article/MED/34364537 https://pubmed.ncbi.nlm.nih.gov/34364537/ https://www.ncbi.nlm.nih.gov/pubmed/34364537 https://pure-portal.regsj.dk/da/publications/variations-in-end-of-life-practices-in-intensive-care-units-world https://boris.unibe.ch/158351/ https://www.sciencedirect.com/science/article/pii/S2213260021002617 https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/88219 https://doi.org/10.1016/s2213-2600(21)00261-7 https://hdl.handle.net/11570/3207622 https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(21)00261-7/abstract https://doi.org/10.1016/S2213-2600(21)00261-7 |
| Rights: | Elsevier TDM |
| Prístupové číslo: | edsair.doi.dedup.....128b5f2bf1eca7de067788f0c6b5e906 |
| Databáza: | OpenAIRE |
Nájsť tento článok vo Web of Science | Abstrakt: | End-of-life practices vary among intensive care units (ICUs) worldwide. Differences can result in variable use of disproportionate or non-beneficial life-sustaining interventions across diverse world regions. This study investigated global disparities in end-of-life practices.In this prospective, multinational, observational study, consecutive adult ICU patients who died or had a limitation of life-sustaining treatment (withholding or withdrawing life-sustaining therapy and active shortening of the dying process) during a 6-month period between Sept 1, 2015, and Sept 30, 2016, were recruited from 199 ICUs in 36 countries. The primary outcome was the end-of-life practice as defined by the end-of-life categories: withholding or withdrawing life-sustaining therapy, active shortening of the dying process, or failed cardiopulmonary resuscitation (CPR). Patients with brain death were included in a separate predefined end-of-life category. Data collection included patient characteristics, diagnoses, end-of-life decisions and their timing related to admission and discharge, or death, with comparisons across different regions. Patients were studied until death or 2 months from the first limitation decision.Of 87 951 patients admitted to ICU, 12 850 (14·6%) were included in the study population. The number of patients categorised into each of the different end-of-life categories were significantly different for each region (p |
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| ISSN: | 22132600 |
| DOI: | 10.1016/s2213-2600(21)00261-7 |