Ascites and spontaneous bacterial peritonitis: An Asian perspective

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Název: Ascites and spontaneous bacterial peritonitis: An Asian perspective
Autoři: Kwang Hyub Han, Jung Min Lee, Sang Hoon Ahn
Přispěvatelé: Jung Min Lee, Kwang-Hyub Han, Sang Hoon Ahn, Ahn, Sang Hoon, Lee, Jung Min, Han, Kwang Hyup
Zdroj: Journal of Gastroenterology and Hepatology. 24:1494-1503
Informace o vydavateli: Wiley, 2009.
Rok vydání: 2009
Témata: Liver Cirrhosis, Asia, Peritonitis/therapy, Liver Cirrhosis/epidemiology, Peritonitis, Ascites/diagnosis, Severity of Illness Index, Ascites/etiology, Peritonitis/diagnosis, Peritonitis/microbiology, Ascites/epidemiology, ascites, 03 medical and health sciences, 0302 clinical medicine, Ascites/therapy, Predictive Value of Tests, Liver Cirrhosis/therapy, Humans, Asia/epidemiology, cirrhosis, Liver Cirrhosis/complications, Ascites, Peritonitis/epidemiology, Combined Modality Therapy, 3. Good health, spontaneous bacterial peritonitis, Asian perspective, Treatment Outcome, Peritonitis/etiology, Disease Progression
Popis: Ascites is the most common complication of liver cirrhosis, and it develops as a consequence of portal hypertension and splanchnic vasodilatation. Depending on severity, management of ascites consists of diverse strategy, including dietary sodium restriction, diuretic therapy, repeated large‐volume paracentesis with albumin infusion, transjugular intrahepatic portosystemic shunt, and liver transplantation. Recently, advances in medical therapy have been made with satavaptan, a V2 receptor antagonist, vasoconstrictors, such as clonidine, midodrine, or terlipressin, and other categories of drugs, including docarpamine and Chinese herbs. These drugs may serve as useful adjuncts to conventional diuretics in the management of ascites. Besides ascites itself, serious complications, such as spontaneous bacterial peritonitis (SBP) and hepatorenal syndrome, frequently ensue in decompensated cirrhosis. SBP develops from the translocation of bacteria from the intestine, and successful management with early diagnosis and treatment with proper prevention in patients of high risk is necessary. In summary, ascites is a starting point for more serious complications in liver cirrhosis. Although liver transplantation is the fundamental treatment, it is not always feasible, and consequently various means of treatment should be used. Further study, particularly in Asia where hepatitis B virus‐related cirrhosis is predominant, is warranted to improve the clinical outcome.
Druh dokumentu: Article
Other literature type
Popis souboru: 1494~1503
Jazyk: English
ISSN: 1440-1746
0815-9319
DOI: 10.1111/j.1440-1746.2009.06020.x
Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/19743995
https://europepmc.org/abstract/MED/19743995
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1440-1746.2009.06020.x
https://pubmed.ncbi.nlm.nih.gov/19743995/
https://yonsei.pure.elsevier.com/en/publications/ascites-and-spontaneous-bacterial-peritonitis-an-asian-perspectiv
http://europepmc.org/abstract/MED/19743995
https://ir.ymlib.yonsei.ac.kr/handle/22282913/104922
https://ir.ymlib.yonsei.ac.kr/handle/22282913/104922
Rights: Wiley Online Library User Agreement
CC BY NC ND
Přístupové číslo: edsair.doi.dedup.....108c6df026d5ee49fd9a8599c7f55698
Databáze: OpenAIRE
Popis
Abstrakt:Ascites is the most common complication of liver cirrhosis, and it develops as a consequence of portal hypertension and splanchnic vasodilatation. Depending on severity, management of ascites consists of diverse strategy, including dietary sodium restriction, diuretic therapy, repeated large‐volume paracentesis with albumin infusion, transjugular intrahepatic portosystemic shunt, and liver transplantation. Recently, advances in medical therapy have been made with satavaptan, a V2 receptor antagonist, vasoconstrictors, such as clonidine, midodrine, or terlipressin, and other categories of drugs, including docarpamine and Chinese herbs. These drugs may serve as useful adjuncts to conventional diuretics in the management of ascites. Besides ascites itself, serious complications, such as spontaneous bacterial peritonitis (SBP) and hepatorenal syndrome, frequently ensue in decompensated cirrhosis. SBP develops from the translocation of bacteria from the intestine, and successful management with early diagnosis and treatment with proper prevention in patients of high risk is necessary. In summary, ascites is a starting point for more serious complications in liver cirrhosis. Although liver transplantation is the fundamental treatment, it is not always feasible, and consequently various means of treatment should be used. Further study, particularly in Asia where hepatitis B virus‐related cirrhosis is predominant, is warranted to improve the clinical outcome.
ISSN:14401746
08159319
DOI:10.1111/j.1440-1746.2009.06020.x