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The effect of a single functional neurology session on thermography of the genital region and sexual function in patients with premature ejaculation

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Title: The effect of a single functional neurology session on thermography of the genital region and sexual function in patients with premature ejaculation
Authors: Vicente Javier Clemente-Suárez, Jorge Rey-Mota, Guillermo Escribano-Colmena, Noelia Vanessa Marín, Jesús Fernandez-Lucas
Contributors: Universidad Complutense de Madrid
Source: Sex Med
Docta Complutense
instname
Publisher Information: Oxford University Press (OUP), 2025.
Publication Year: 2025
Subject Terms: Genital blood flow, Salud pública (Medicina), Premature ejaculation, Medio ambiente natural, 3205 Medicina Interna, 612.669.7, 2415 Biología Molecular, Bioquímica (Biología), 2411 Fisiología Humana, Functional neurology, Intravaginal ejaculatory latency time, Thermography, Neurociencias (Biológicas), 2490 Neurociencias, Vascular regulation, Autonomic nervous system, Ejaculation, 2414 Microbiología, 612.82, 613.956, Original Research
Description: Background Premature ejaculation (PE) is a common male sexual dysfunction with limited long-term therapeutic options. Pharmacological and behavioral treatments often yield only temporary improvement, and alternative neuromodulatory strategies remain underexplored. Functional neurology, which targets autonomic and sensory-motor regulation, may offer a novel approach. Aim To evaluate the effect of a single functional neurology intervention on genital thermoregulation and ejaculatory latency in men with PE. Methods Fifty-two men diagnosed with PE participated in a pre–post intervention study. Each underwent a single session of functional neurology aimed at modulating nociceptor and mechanoreceptor pathways. Genital thermoregulation was assessed using infrared thermography, and ejaculatory function was measured via intravaginal ejaculatory latency time (IELT) and self-report at baseline, after the first post-treatment sexual encounter, and at 1-month follow-up. Statistical analyses included repeated-measures ANOVA, paired t-tests, Pearson correlation, and multiple regression. Outcomes Significant improvements in IELT and genital temperature were expected following the intervention, supporting its role in enhancing autonomic regulation and microvascular circulation. Results Intravaginal ejaculatory latency time increased significantly from a baseline of 20.4 ± 11.5 seconds to 439.2 ± 214.5 seconds post-treatment, with sustained effects at 1 month (498.0 ± 171.6 seconds; P Clinical Implications Functional neurology may be a non-invasive, fast-acting intervention for improving ejaculatory control in PE by promoting autonomic balance and vascular function. Thermography proved useful as a biomarker for physiological changes and treatment efficacy. Strengths and Limitations This study is the first to evaluate thermographic and ejaculatory outcomes after a functional neurology intervention in PE. Strengths include objective and subjective measures, while limitations involve the lack of a control group, small sample size, and short-term follow-up. These results should be confirmed through randomized controlled trials. Conclusion A single session of functional neurology significantly improved both genital thermoregulation and ejaculatory latency in men with PE. These findings support the integration of neuromodulatory techniques into multidisciplinary strategies for sexual dysfunction treatment.
Document Type: Article
Other literature type
File Description: application/pdf
Language: English
ISSN: 2050-1161
DOI: 10.1093/sexmed/qfaf046
Access URL: https://hdl.handle.net/20.500.14352/123150
Rights: CC BY NC
URL: http://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.
Accession Number: edsair.doi.dedup.....10320f1e2acab25f3d8d6ccc38b591f3
Database: OpenAIRE
Description
Abstract:Background Premature ejaculation (PE) is a common male sexual dysfunction with limited long-term therapeutic options. Pharmacological and behavioral treatments often yield only temporary improvement, and alternative neuromodulatory strategies remain underexplored. Functional neurology, which targets autonomic and sensory-motor regulation, may offer a novel approach. Aim To evaluate the effect of a single functional neurology intervention on genital thermoregulation and ejaculatory latency in men with PE. Methods Fifty-two men diagnosed with PE participated in a pre–post intervention study. Each underwent a single session of functional neurology aimed at modulating nociceptor and mechanoreceptor pathways. Genital thermoregulation was assessed using infrared thermography, and ejaculatory function was measured via intravaginal ejaculatory latency time (IELT) and self-report at baseline, after the first post-treatment sexual encounter, and at 1-month follow-up. Statistical analyses included repeated-measures ANOVA, paired t-tests, Pearson correlation, and multiple regression. Outcomes Significant improvements in IELT and genital temperature were expected following the intervention, supporting its role in enhancing autonomic regulation and microvascular circulation. Results Intravaginal ejaculatory latency time increased significantly from a baseline of 20.4 ± 11.5 seconds to 439.2 ± 214.5 seconds post-treatment, with sustained effects at 1 month (498.0 ± 171.6 seconds; P Clinical Implications Functional neurology may be a non-invasive, fast-acting intervention for improving ejaculatory control in PE by promoting autonomic balance and vascular function. Thermography proved useful as a biomarker for physiological changes and treatment efficacy. Strengths and Limitations This study is the first to evaluate thermographic and ejaculatory outcomes after a functional neurology intervention in PE. Strengths include objective and subjective measures, while limitations involve the lack of a control group, small sample size, and short-term follow-up. These results should be confirmed through randomized controlled trials. Conclusion A single session of functional neurology significantly improved both genital thermoregulation and ejaculatory latency in men with PE. These findings support the integration of neuromodulatory techniques into multidisciplinary strategies for sexual dysfunction treatment.
ISSN:20501161
DOI:10.1093/sexmed/qfaf046