Pulp Revascularization of Immature Teeth With Apical Periodontitis: A Clinical Study

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Bibliographic Details
Title: Pulp Revascularization of Immature Teeth With Apical Periodontitis: A Clinical Study
Authors: Ding, RY, Wang, QQ, Zhang, CF, Yin, XZ, Cheung, GSp, Chen, J
Source: Journal of Endodontics. 35:745-749
Publisher Information: Elsevier BV, 2009.
Publication Year: 2009
Subject Terms: Male, Aluminum Compounds - therapeutic use, Bicuspid - pathology, Tooth Apex - physiopathology, Minocycline, Minocycline - administration & dosage, Root Canal Therapy - methods, Odontogenesis - physiology, 03 medical and health sciences, 0302 clinical medicine, Physiologic - physiology, Silicates - therapeutic use, Anti-Infective Agents, Ciprofloxacin, Metronidazole, Calcium Compounds - therapeutic use, Anti-Bacterial Agents - administration & dosage, Dental Pulp Necrosis, Humans, Bicuspid, Aluminum Compounds, Child, Blood Coagulation, Neovascularization, Anti-Infective Agents - administration & dosage, Incisor - pathology, Dental Pulp, Blood Coagulation - physiology, Dental Pulp Necrosis - therapy, Guided Tissue Regeneration, Oxides - therapeutic use, Periapical Periodontitis - therapy, Root Canal Preparation - methods, Calcium Compounds, Root Canal Filling Materials - therapeutic use, Anti-Bacterial Agents, Guided Tissue Regeneration - methods, Incisor, Drug Combinations, Treatment Outcome, Ciprofloxacin - administration & dosage, Neovascularization, Physiologic - physiology, Female, Metronidazole - administration & dosage, Dental Pulp Cavity, Dental Pulp Cavity - blood supply, Dental Pulp - blood supply - physiopathology, Follow-Up Studies
Description: The purpose of this study was to examine the effect of a pulpal revascularization procedure for immature necrotic teeth with apical periodontitis.Twelve patients, each with an immature permanent tooth with chronic or acute apical periodontitis, were recruited. A triantibiotic mix (ciprofloxacin, metronidazole, and minocycline) was used to disinfect the pulp for 1 week. Then a blood clot was created in the canal, over which grey mineral trioxide aggregate was placed. Patients were recalled periodically.Six patients dropped from the study (as a result of pain or failure to induce bleeding after canal disinfection) and instead received a standard apexification procedure. Another 3 patients did not attend any recall appointments. The remaining teeth (n = 3) were found to exhibit complete root development, with a positive response to pulp testing.Revascularization could be effective for managing immature permanent teeth with apical periodontitis with appropriate case selection.
Document Type: Article
Language: English
ISSN: 0099-2399
DOI: 10.1016/j.joen.2009.02.009
Access URL: https://pubmed.ncbi.nlm.nih.gov/19410097
http://hub.hku.hk/handle/10722/58035
https://core.ac.uk/display/155470609
http://europepmc.org/abstract/MED/19410097
https://www.sciencedirect.com/science/article/pii/S009923990900137X
https://www.ncbi.nlm.nih.gov/pubmed/19410097
https://pubmed.ncbi.nlm.nih.gov/19410097/
http://hdl.handle.net/10722/58035
Rights: Elsevier TDM
Accession Number: edsair.doi.dedup.....0e632a1608f9e937c07fd863f0c68477
Database: OpenAIRE
Description
Abstract:The purpose of this study was to examine the effect of a pulpal revascularization procedure for immature necrotic teeth with apical periodontitis.Twelve patients, each with an immature permanent tooth with chronic or acute apical periodontitis, were recruited. A triantibiotic mix (ciprofloxacin, metronidazole, and minocycline) was used to disinfect the pulp for 1 week. Then a blood clot was created in the canal, over which grey mineral trioxide aggregate was placed. Patients were recalled periodically.Six patients dropped from the study (as a result of pain or failure to induce bleeding after canal disinfection) and instead received a standard apexification procedure. Another 3 patients did not attend any recall appointments. The remaining teeth (n = 3) were found to exhibit complete root development, with a positive response to pulp testing.Revascularization could be effective for managing immature permanent teeth with apical periodontitis with appropriate case selection.
ISSN:00992399
DOI:10.1016/j.joen.2009.02.009