Effects of red ginseng on the elastic properties of human skin
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| Názov: | Effects of red ginseng on the elastic properties of human skin |
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| Autori: | Jin-Woo Lee, Donggerami Moon, Moon Young Park, Kyung Sook Kim, Se Jik Han, Sangwoo Kwon |
| Zdroj: | J Ginseng Res Journal of Ginseng Research, Vol 44, Iss 5, Pp 738-746 (2020) |
| Informácie o vydavateľovi: | Elsevier BV, 2020. |
| Rok vydania: | 2020 |
| Predmety: | 0301 basic medicine, Atomic force microscopy, 0303 health sciences, 03 medical and health sciences, QK1-989, Cellular stiffness, Botany, Collagen, Red ginseng, Skin elasticity, Pharmacology & Physiology, 3. Good health |
| Popis: | Red ginseng contains components, including microelements, vitamins, essential oils, and fatty acids, that can be used in skincare to delay the aging process. We investigated the effects of red ginseng treatment on skin elasticity by assessing cellular stiffness and measuring collagen protein synthesis.Human dermal fibroblasts were treated with red ginseng, and the resulting changes in stiffness were investigated using atomic force microscopy. Cytoskeletal changes and mRNA expression of biomarkers of aging, including that of procollagens I and VII, elastin, and fibrillin-1, were investigated. Collagen in a human skin equivalent treated with red ginseng was visualized via hematoxylin and eosin staining, scanning electron microscopy, and atomic force microscopy.The stiffness of fibroblasts was significantly reduced by treatment with red ginseng concentrations of ≥ 0.8 mg/mL. The ratio of F-actin to G-actin decreased after treatment, which corresponded to a change in fibroblast stiffness. The storage modulus (G') and loss modulus (G″) of the skin equivalent were both lowered by red ginseng treatment. This result indicates that the viscoelasticity of the skin equivalent can be restored by red ginseng treatment. |
| Druh dokumentu: | Article Other literature type |
| Jazyk: | English |
| ISSN: | 1226-8453 |
| DOI: | 10.1016/j.jgr.2019.08.004 |
| Prístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/32913403 https://doaj.org/article/7c3e1f6b8bdf4478932254171b61d950 https://www.sciencedirect.com/science/article/abs/pii/S1226845319300478 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471210 https://www.sciencedirect.com/science/article/pii/S1226845319300478 https://pubmed.ncbi.nlm.nih.gov/32913403/ |
| Rights: | CC BY NC ND |
| Prístupové číslo: | edsair.doi.dedup.....084c2d59ddbd2d895d02c290bdc1f949 |
| Databáza: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstrakt: | Red ginseng contains components, including microelements, vitamins, essential oils, and fatty acids, that can be used in skincare to delay the aging process. We investigated the effects of red ginseng treatment on skin elasticity by assessing cellular stiffness and measuring collagen protein synthesis.Human dermal fibroblasts were treated with red ginseng, and the resulting changes in stiffness were investigated using atomic force microscopy. Cytoskeletal changes and mRNA expression of biomarkers of aging, including that of procollagens I and VII, elastin, and fibrillin-1, were investigated. Collagen in a human skin equivalent treated with red ginseng was visualized via hematoxylin and eosin staining, scanning electron microscopy, and atomic force microscopy.The stiffness of fibroblasts was significantly reduced by treatment with red ginseng concentrations of ≥ 0.8 mg/mL. The ratio of F-actin to G-actin decreased after treatment, which corresponded to a change in fibroblast stiffness. The storage modulus (G') and loss modulus (G″) of the skin equivalent were both lowered by red ginseng treatment. This result indicates that the viscoelasticity of the skin equivalent can be restored by red ginseng treatment. |
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| ISSN: | 12268453 |
| DOI: | 10.1016/j.jgr.2019.08.004 |