Multiparametric Assessment of Right Ventricular Dysfunction in Heart Failure: An Analysis From PARAGON‐HF

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Názov: Multiparametric Assessment of Right Ventricular Dysfunction in Heart Failure: An Analysis From PARAGON‐HF
Autori: Henri Lu, Riccardo M. Inciardi, Martin Abanda, Amil M. Shah, Maja Cikes, Brian L. Claggett, Narayana Prasad, Carolyn S. P. Lam, Margaret Redfield, John J. V. McMurray, Marc A. Pfeffer, Scott D. Solomon, Sheila M. Hegde, Hicham Skali
Zdroj: J Am Heart Assoc
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 14, Iss 1 (2025)
Journal of the American Heart Association, vol. 14, no. 1, pp. e037380
Informácie o vydavateľovi: Ovid Technologies (Wolters Kluwer Health), 2025.
Rok vydania: 2025
Predmety: heart failure with preserved ejection fraction, Male, Stroke Volume / physiology, Ventricular Dysfunction, Right, Humans, Female, Heart Failure/physiopathology, Heart Failure/mortality, Aged, Ventricular Dysfunction, Right/physiopathology, Ventricular Dysfunction, Right/diagnostic imaging, Stroke Volume/physiology, Ventricular Function, Right/physiology, Prospective Studies, Aged, 80 and over, Prognosis, Echocardiography, Angiotensin Receptor Antagonists/therapeutic use, Middle Aged, Predictive Value of Tests, Hospitalization/statistics & numerical data, echocardiography, right ventricular dysfunction, sacubitril/valsartan, heart failure, Angiotensin Receptor Antagonists, 03 medical and health sciences, 0302 clinical medicine, Hospitalization / statistics & numerical data, Heart Failure / physiopathology, Diseases of the circulatory (Cardiovascular) system, Original Research, Heart Failure, Ventricular Dysfunction, Right / diagnostic imaging, Ventricular Dysfunction, Right / physiopathology, Angiotensin Receptor Antagonists / therapeutic use, Stroke Volume, Hospitalization, Ventricular Function, Right / physiology, RC666-701, Ventricular Function, Right, Heart Failure / mortality
Popis: Background This study aims to characterize right ventricular dysfunction (RVD) in heart failure (HF) with preserved ejection fraction and understand the cumulative prognostic value of abnormal RV echocardiographic parameters in HF with preserved ejection fraction. Methods and Results Data from 809 patients in the PARAGON‐HF (Prospective Comparison of Angiotensin Receptor–Neprilysin Inhibitor With Angiotensin‐Receptor Blocker Global Outcomes in HF With Preserved Ejection Fraction) echocardiographic substudy (55% women, mean age 74±8 years) were analyzed. Correlates of RVD (defined as tricuspid annular plane systolic excursion Conclusions RV measures may underestimate the burden of RVD in HF with preserved ejection fraction when considered in isolation. Clinicians should consider multiple dimensions to comprehensively assess RV function in patients with HF with preserved ejection fraction.
Druh dokumentu: Article
Other literature type
Popis súboru: application/pdf
Jazyk: English
ISSN: 2047-9980
DOI: 10.1161/jaha.124.037380
Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39719412
https://doaj.org/article/9fe830ba59d34b2dbc98214d4cac3db6
https://www.ahajournals.org/doi/10.1161/JAHA.124.037380
https://doi.org/10.1161/jaha.124.037380
https://serval.unil.ch/resource/serval:BIB_06ECE10BCD80.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_06ECE10BCD80
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_06ECE10BCD808
https://urn.nsk.hr/urn:nbn:hr:105:962648
https://doi.org/10.1161/jaha.124.037380
Rights: CC BY NC ND
URL: http://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
Prístupové číslo: edsair.doi.dedup.....060f5c2269ca7887e3fa2ca719f29b1a
Databáza: OpenAIRE
Popis
Abstrakt:Background This study aims to characterize right ventricular dysfunction (RVD) in heart failure (HF) with preserved ejection fraction and understand the cumulative prognostic value of abnormal RV echocardiographic parameters in HF with preserved ejection fraction. Methods and Results Data from 809 patients in the PARAGON‐HF (Prospective Comparison of Angiotensin Receptor–Neprilysin Inhibitor With Angiotensin‐Receptor Blocker Global Outcomes in HF With Preserved Ejection Fraction) echocardiographic substudy (55% women, mean age 74±8 years) were analyzed. Correlates of RVD (defined as tricuspid annular plane systolic excursion Conclusions RV measures may underestimate the burden of RVD in HF with preserved ejection fraction when considered in isolation. Clinicians should consider multiple dimensions to comprehensively assess RV function in patients with HF with preserved ejection fraction.
ISSN:20479980
DOI:10.1161/jaha.124.037380