The HOPE cohort: cohort profile and evaluation of selection bias: cohort profile and evaluation of selection bias

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Title: The HOPE cohort: cohort profile and evaluation of selection bias: cohort profile and evaluation of selection bias
Authors: Mette-Marie Zacher Kjeldsen, Merete Lund Mægbæk, Xiaoqin Liu, Malene Galle Madsen, Mette Bliddal, Sofie Egsgaard, Kathrine Bang Madsen, Trine Munk-Olsen
Source: Eur J Epidemiol
Kjeldsen, M-M Z, Mægbæk, M L, Liu, X, Madsen, M G, Bliddal, M, Egsgaard, S, Bang Madsen, K & Munk-Olsen, T 2024, 'The HOPE cohort : cohort profile and evaluation of selection bias', European Journal of Epidemiology, vol. 39, no. 8, pp. 943-954. https://doi.org/10.1007/s10654-024-01150-4
Publisher Information: Springer Science and Business Media LLC, 2024.
Publication Year: 2024
Subject Terms: Edinburgh postnatal depression scale, Adult, Cohort Profile, Adolescent, Depression, Denmark, Mothers, Cohort profile, Mothers/psychology, Denmark/epidemiology, 3. Good health, Depression, Postpartum, Cohort Studies, Young Adult, Socioeconomic Factors, Pregnancy, Postpartum depression, Humans, Female, Registries, Postpartum/epidemiology, Selection, Selection Bias
Description: The HOPE cohort is a Danish nationwide cohort with ongoing follow-up, holding information on postpartum depression (PPD) symptoms and diagnoses on 170,218 childbirths (142,795 unique mothers). These data have been linked with extensive register data on health and socioeconomic information on the mothers, their partners, parents, and children. This cohort profile aimed to provide an overview of the data collection and content, describe characteristics, and evaluate potential selection bias. PPD screenings, using the Edinburgh Postnatal Depression Scale, were collected from 67 of the 98 Danish municipalities, covering the period January 2015 to December 2021. This data was linked with register data on PPD diagnoses (identified through medication prescriptions and hospital contacts) as well as background information. Cohort characteristics were compared to the source population, defined as all childbirths by women residing in Denmark during the same period (452,207 childbirths). Potential selection bias was evaluated by comparing odds ratios of five well-established associations between the cohort and the source population. The HOPE cohort holds information on 170,218 childbirths (38% of the source population) involving 142,795 unique mothers. The HOPE cohort only differed slightly from the source population on most characteristics examined, but larger differences were observed on specific characteristics with an underrepresentation of the youngest and oldest age groups, women with more than three children or twins/triplets, and women born outside Denmark. Similar associations were identified across the two populations within the five well-established associations. There was no indication of selection bias on the five examined associations, and the HOPE cohort is representative of the source population on important perinatal characteristics.
Document Type: Article
Other literature type
File Description: application/pdf
Language: English
ISSN: 1573-7284
0393-2990
DOI: 10.1007/s10654-024-01150-4
Access URL: https://pubmed.ncbi.nlm.nih.gov/39158818
https://pure.au.dk/ws/files/433475383/The_HOPE_cohort_cohort_profile_and_evaluation_of_selection_bias.pdf
https://portal.findresearcher.sdu.dk/da/publications/9d90381d-abd7-48a8-8a3a-eb67a58d2c64
https://doi.org/10.1007/s10654-024-01150-4
https://pure.au.dk/ws/files/433475383/The_HOPE_cohort_cohort_profile_and_evaluation_of_selection_bias.pdf
https://doi.org/10.1007/s10654-024-01150-4
http://www.scopus.com/inward/record.url?scp=85201559056&partnerID=8YFLogxK
https://pure.au.dk/portal/en/publications/ac62a6a8-11c9-4440-a92f-eda61d40470c
Rights: CC BY
Accession Number: edsair.doi.dedup.....0546053ad5a17d460a7dfc3e350decad
Database: OpenAIRE
Description
Abstract:The HOPE cohort is a Danish nationwide cohort with ongoing follow-up, holding information on postpartum depression (PPD) symptoms and diagnoses on 170,218 childbirths (142,795 unique mothers). These data have been linked with extensive register data on health and socioeconomic information on the mothers, their partners, parents, and children. This cohort profile aimed to provide an overview of the data collection and content, describe characteristics, and evaluate potential selection bias. PPD screenings, using the Edinburgh Postnatal Depression Scale, were collected from 67 of the 98 Danish municipalities, covering the period January 2015 to December 2021. This data was linked with register data on PPD diagnoses (identified through medication prescriptions and hospital contacts) as well as background information. Cohort characteristics were compared to the source population, defined as all childbirths by women residing in Denmark during the same period (452,207 childbirths). Potential selection bias was evaluated by comparing odds ratios of five well-established associations between the cohort and the source population. The HOPE cohort holds information on 170,218 childbirths (38% of the source population) involving 142,795 unique mothers. The HOPE cohort only differed slightly from the source population on most characteristics examined, but larger differences were observed on specific characteristics with an underrepresentation of the youngest and oldest age groups, women with more than three children or twins/triplets, and women born outside Denmark. Similar associations were identified across the two populations within the five well-established associations. There was no indication of selection bias on the five examined associations, and the HOPE cohort is representative of the source population on important perinatal characteristics.
ISSN:15737284
03932990
DOI:10.1007/s10654-024-01150-4