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Drug Delivery in Retinoblastoma

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Název:	Drug Delivery in Retinoblastoma
Autoři:	Steven Trinh, Amit Joshi, Shyam S. Chaurasia, Aparna Ramasubramanian
Zdroj:	International Ophthalmology Clinics. 65:51-59
Informace o vydavateli:	Ovid Technologies (Wolters Kluwer Health), 2025.
Rok vydání:	2025
Popis:	Retinoblastoma is considered a prototype pediatric malignancy as retinoblastoma research has been instrumental in advancing our knowledge of cancer genetics, tumor suppressor genes, and the development of new treatment approaches. Also, retinoblastoma boasts one of the highest survival rates among pediatric cancers, with survival rates often exceeding 90% in developed countries. The research focus is shifting towards improved globe and vision salvage. Also, there is emphasis on advancing treatments that are tailored based on individual patient characteristics, including tumor genetics and molecular markers, to improve outcomes and minimize side effects.
Druh dokumentu:	Article
Jazyk:	English
ISSN:	1536-9617 0020-8167
DOI:	10.1097/iio.0000000000000590
Přístupové číslo:	edsair.doi...........d86fdd9f3bdfb1701056e69c60e9c4cf
Databáze:	OpenAIRE

Popis
Abstrakt:	Retinoblastoma is considered a prototype pediatric malignancy as retinoblastoma research has been instrumental in advancing our knowledge of cancer genetics, tumor suppressor genes, and the development of new treatment approaches. Also, retinoblastoma boasts one of the highest survival rates among pediatric cancers, with survival rates often exceeding 90% in developed countries. The research focus is shifting towards improved globe and vision salvage. Also, there is emphasis on advancing treatments that are tailored based on individual patient characteristics, including tumor genetics and molecular markers, to improve outcomes and minimize side effects.
ISSN:	15369617 00208167
DOI:	10.1097/iio.0000000000000590