Powder diffraction
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| Title: | Powder diffraction |
|---|---|
| Authors: | John R Helliwell |
| Source: | Precision and Accuracy in Biological Crystallography, Diffraction, Scattering, Microscopies, and Spectroscopies ISBN: 9780198952824 |
| Publisher Information: | Oxford University PressOxford, 2025. |
| Publication Year: | 2025 |
| Description: | Powder diffraction is essential in patenting pharmaceutical tablets as the regulatory authorities require characterization of what a patient actually consumes. Diffraction measurements are from a crushed tablet of the drug in the form in which the patient is taking it for their disease or ailment. There are many well-documented examples of such pharmaceutically important polymorphs. An interesting recent case is that of psilocybin {systematic name: 3-[2-(dimethylamino)ethyl]-1H-indol-4-yl dihydrogen phosphate) which is a zwitterionic tryptamine natural product found in numerous species of fungi known for their psychoactive properties. Protein powder diffraction is a more specialist application; insulin, a very important medicine, is an interesting example of this. |
| Document Type: | Part of book or chapter of book |
| Language: | English |
| DOI: | 10.1093/9780198952831.003.0009 |
| Accession Number: | edsair.doi...........be778a26bcce8ee559fdd8bc64336550 |
| Database: | OpenAIRE |
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