View in EDS

Powder diffraction

Saved in:
Bibliographic Details
Title: Powder diffraction
Authors: John R Helliwell
Source: Precision and Accuracy in Biological Crystallography, Diffraction, Scattering, Microscopies, and Spectroscopies ISBN: 9780198952824
Publisher Information: Oxford University PressOxford, 2025.
Publication Year: 2025
Description: Powder diffraction is essential in patenting pharmaceutical tablets as the regulatory authorities require characterization of what a patient actually consumes. Diffraction measurements are from a crushed tablet of the drug in the form in which the patient is taking it for their disease or ailment. There are many well-documented examples of such pharmaceutically important polymorphs. An interesting recent case is that of psilocybin {systematic name: 3-[2-(dimethylamino)ethyl]-1H-indol-4-yl dihydrogen phosphate) which is a zwitterionic tryptamine natural product found in numerous species of fungi known for their psychoactive properties. Protein powder diffraction is a more specialist application; insulin, a very important medicine, is an interesting example of this.
Document Type: Part of book or chapter of book
Language: English
DOI: 10.1093/9780198952831.003.0009
Accession Number: edsair.doi...........be778a26bcce8ee559fdd8bc64336550
Database: OpenAIRE
Description
Abstract:Powder diffraction is essential in patenting pharmaceutical tablets as the regulatory authorities require characterization of what a patient actually consumes. Diffraction measurements are from a crushed tablet of the drug in the form in which the patient is taking it for their disease or ailment. There are many well-documented examples of such pharmaceutically important polymorphs. An interesting recent case is that of psilocybin {systematic name: 3-[2-(dimethylamino)ethyl]-1H-indol-4-yl dihydrogen phosphate) which is a zwitterionic tryptamine natural product found in numerous species of fungi known for their psychoactive properties. Protein powder diffraction is a more specialist application; insulin, a very important medicine, is an interesting example of this.
DOI:10.1093/9780198952831.003.0009