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Multifaceted mutational immunotherapeutic approach to design therapeutic mAbs to combat monkeypox disease via integrated screening algorithms and antibody engineering

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Titel: Multifaceted mutational immunotherapeutic approach to design therapeutic mAbs to combat monkeypox disease via integrated screening algorithms and antibody engineering
Autoren: Satyendra Singh, Abhishek Rao, Anshuman Mishra, Amit Mishra, Vijay Kumar Prajapati
Quelle: Molecular Systems Design & Engineering. 8:1301-1318
Verlagsinformationen: Royal Society of Chemistry (RSC), 2023.
Publikationsjahr: 2023
Schlagwörter: 3. Good health
Beschreibung: Development of therapeutic mAbs against the monkeypox virus targeting critical enzymes. The mutational immunotherapy improves the efficacy. This study provides potential therapy, emphasizing the advantages of mAbs over small molecule inhibitors.
Publikationsart: Article
Sprache: English
ISSN: 2058-9689
DOI: 10.1039/d3me00059a
Rights: Royal Society of Chemistry Licence to Publish
Dokumentencode: edsair.doi...........4066300f56463d43f21d33e7ce41a4db
Datenbank: OpenAIRE
Beschreibung
Abstract:Development of therapeutic mAbs against the monkeypox virus targeting critical enzymes. The mutational immunotherapy improves the efficacy. This study provides potential therapy, emphasizing the advantages of mAbs over small molecule inhibitors.
ISSN:20589689
DOI:10.1039/d3me00059a