Bibliographic Details
| Title: |
Brain Derived Neurotrophic Factor and cognitive markers in subjects with Alzheimer’s disease |
| Authors: |
Naybí Prendes Rivero, Levis Verde Corvo, Belkis López González, Iris Dany Carmenate Rodríguez, Nibaldo B Mesa Hernández, María A Robinson Agramonte |
| Source: |
Revista Habanera de Ciencias Médicas, Vol 22, Iss 5, Pp e5179-e5179 (2024) |
| Publisher Information: |
Universidad de Ciencias Médicas de La Habana, 2024. |
| Publication Year: |
2024 |
| Subject Terms: |
Medicine (General), factor neurotrófico derivado del cerebro, R5-920, función ejecutiva, enfermedad de alzheimer, memoria episódica, Public aspects of medicine, RA1-1270, deterioro cognitivo leve |
| Description: |
Introduction: The brain derived neurotrophic factor is a neurotrophin modulator of cognitive processes. Current studies in Alzheimer’s disease patients show alterations in biomarkers at outlying levels. Objective: To analyze the association between the serum brain-derived neurotrophic factor levels and the cognitive markers in Alzheimer’s disease subjects. Material and Methods: A correlational transversal study was conducted in subjects aged 64 years, distributed into three groups: group 1ː16 controls, group 2ː27 with mild cognitive impairment, and group 3ː21 with Alzheimer’s disease. A neuropsychological test battery, and the immunoenzymatic method (ELISA), Promega Emax Kit were applied to determine the serum brain-derived neurotrophic factor levels. The statistical analysis of data was performed using the one-way ANOVA test, the post-hoc Dunnett´s test and the Pearson’s correlation coefficient (p |
| Document Type: |
Article |
| Language: |
English |
| ISSN: |
1729-519X |
| Access URL: |
https://doaj.org/article/0ef0af1b7c7b42b0babd1b4908e5cfed |
| Accession Number: |
edsair.doajarticles..a6ae7d01a2846656bb0b523975ea79eb |
| Database: |
OpenAIRE |
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