EXERCISE-INDUCED BRONCHOCONSTRICTION: PATHOGENESIS, SYMPTOMS, DIAGNOSIS AND CURRENT TREATMENT - LITERATURE REVIEW
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| Názov: | EXERCISE-INDUCED BRONCHOCONSTRICTION: PATHOGENESIS, SYMPTOMS, DIAGNOSIS AND CURRENT TREATMENT - LITERATURE REVIEW |
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| Autori: | Izabela Szczap, Adam Żuczek, Olga Żuczek, Kinga Dyndał, Marcelina Broda, Katarzyna Urbańska, Anna Hawryluk, Kamil Marzec, Aleksandra Mokrzycka, Patrycja Jędrzejewska-Rzezak |
| Zdroj: | International Journal of Innovative Technologies in Social Science; Vol 4 No 3(47) (2025): International Journal of Innovative Technologies in Social Science International Journal of Innovative Technologies in Social Science; Том 4 № 3(47) (2025): International Journal of Innovative Technologies in Social Science |
| Informácie o vydavateľovi: | RS Global Sp. z O.O., 2025. |
| Rok vydania: | 2025 |
| Predmety: | Exercise-Induced Bronchoconstriction, Exercise-Induced Asthma, EIB, Asthma, Bronchoconstriction |
| Popis: | Objective: Exercise-induced bronchoconstriction (EIB) is a reversible narrowing of the airways that occurs during or shortly after physical exertion, affecting both individuals with asthma and those without prior respiratory diagnoses. EIB is particularly prevalent among athletes and individuals exposed to cold, dry air or environmental pollutants. This article aims to present an updated review of EIB, focusing on its underlying mechanisms, clinical symptoms, diagnostic approaches, and current treatment options. Methods: A comprehensive review of recent literature was conducted, examining the pathophysiology, clinical manifestations, diagnostic criteria, and management strategies of EIB. The search incorporated studies addressing both pharmacological and non-pharmacological interventions, as well as diagnostic methodologies such as spirometry and bronchial provocation tests. Key findings: EIB primarily results from airway dehydration and cooling during exercise, triggering the release of inflammatory mediators like leukotrienes and prostaglandins that cause bronchoconstriction. Patients typically experience symptoms including shortness of breath, wheezing, cough, and chest tightness, which can severely impact exercise performance and quality of life. Diagnosis is best established through objective lung function testing, with a fall in FEV1 by 10% or more after exercise being indicative of EIB. Inhaled short-acting β2-agonists remain the cornerstone of treatment, while inhaled corticosteroids and leukotriene receptor antagonists serve as adjunct therapies in cases with underlying asthma or persistent symptoms. Conclusions: Accurate diagnosis and tailored management are essential to enable individuals with EIB to engage safely in physical activities. Combining pharmacological treatments with lifestyle modifications provides effective symptom control. Ongoing research is warranted to refine diagnostic tools and optimize therapeutic protocols to further improve outcomes for affected individuals. |
| Druh dokumentu: | Article |
| Popis súboru: | application/pdf |
| Jazyk: | English |
| ISSN: | 2544-9338 2544-9435 |
| DOI: | 10.31435/ijitss.3(47).2025.3899 |
| Prístupová URL adresa: | https://rsglobal.pl/index.php/ijitss/article/view/3899 |
| Rights: | CC BY |
| Prístupové číslo: | edsair.07b5c0ccd4fe..40f62a3a5e81cd3437c03a7e0fe357ed |
| Databáza: | OpenAIRE |
Nájsť tento článok vo Web of Science | Abstrakt: | Objective: Exercise-induced bronchoconstriction (EIB) is a reversible narrowing of the airways that occurs during or shortly after physical exertion, affecting both individuals with asthma and those without prior respiratory diagnoses. EIB is particularly prevalent among athletes and individuals exposed to cold, dry air or environmental pollutants. This article aims to present an updated review of EIB, focusing on its underlying mechanisms, clinical symptoms, diagnostic approaches, and current treatment options. Methods: A comprehensive review of recent literature was conducted, examining the pathophysiology, clinical manifestations, diagnostic criteria, and management strategies of EIB. The search incorporated studies addressing both pharmacological and non-pharmacological interventions, as well as diagnostic methodologies such as spirometry and bronchial provocation tests. Key findings: EIB primarily results from airway dehydration and cooling during exercise, triggering the release of inflammatory mediators like leukotrienes and prostaglandins that cause bronchoconstriction. Patients typically experience symptoms including shortness of breath, wheezing, cough, and chest tightness, which can severely impact exercise performance and quality of life. Diagnosis is best established through objective lung function testing, with a fall in FEV1 by 10% or more after exercise being indicative of EIB. Inhaled short-acting β2-agonists remain the cornerstone of treatment, while inhaled corticosteroids and leukotriene receptor antagonists serve as adjunct therapies in cases with underlying asthma or persistent symptoms. Conclusions: Accurate diagnosis and tailored management are essential to enable individuals with EIB to engage safely in physical activities. Combining pharmacological treatments with lifestyle modifications provides effective symptom control. Ongoing research is warranted to refine diagnostic tools and optimize therapeutic protocols to further improve outcomes for affected individuals. |
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| ISSN: | 25449338 25449435 |
| DOI: | 10.31435/ijitss.3(47).2025.3899 |