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A study of Differentiation of Liver Metastases and Primary Hepatic Malignancies Using Diffusion-Weighted MRI and ADC Measurements in a tertiary hospital in Central India.

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Názov: A study of Differentiation of Liver Metastases and Primary Hepatic Malignancies Using Diffusion-Weighted MRI and ADC Measurements in a tertiary hospital in Central India.
Autori: Tekam, Sharda, Yerme, Pravin, Gandhi, Pranay
Zdroj: European Journal of Cardiovascular Medicine; Nov2025, Vol. 15 Issue 11, p47-56, 10p
Predmety: LIVER metastasis, DIFFUSION magnetic resonance imaging, LIVER cancer, DIAGNOSTIC services, CHOLANGIOCARCINOMA, HEPATOCELLULAR carcinoma, PATIENT care, DIFFUSION measurements
Abstrakt: Background: Purpose: To quantitatively assess the diagnostic value of DWI and ADC mapping in distinguishing liver metastases from primary hepatic malignancies (hepatocellular carcinoma and cholangiocarcinoma). Methods: DW-MRI data from patients with biopsy-proven malignant liver lesions were retrospectively analyzed. ADC values of metastatic lesions were compared to those of HCC and cholangiocarcinoma using t-tests and ROC analysis. Results: Mean ADC of metastases (0.81±0.19×10−3 mm2/s0.81±0.19×10−3mm2/s) was significantly lower than that of HCC (1.03±0.23×10−3 mm2/s1.03±0.23×10−3mm2/s), p=0.01. ROC analysis produced an AUC of 0.83 and an optimal cutoff of 0.90×10−3 mm2/s0.90×10−3mm2/s for identifying metastases Conclusion: DW-MRI ADC quantification is a practical adjunct for differentiating metastatic lesions from primary hepatic cancers, supporting more precise patient management. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Cardiovascular Medicine is the property of Healthcare Bulletin and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: A study of Differentiation of Liver Metastases and Primary Hepatic Malignancies Using Diffusion-Weighted MRI and ADC Measurements in a tertiary hospital in Central India.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Tekam%2C+Sharda%22">Tekam, Sharda</searchLink><br /><searchLink fieldCode="AR" term="%22Yerme%2C+Pravin%22">Yerme, Pravin</searchLink><br /><searchLink fieldCode="AR" term="%22Gandhi%2C+Pranay%22">Gandhi, Pranay</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: European Journal of Cardiovascular Medicine; Nov2025, Vol. 15 Issue 11, p47-56, 10p
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22LIVER+metastasis%22">LIVER metastasis</searchLink><br /><searchLink fieldCode="DE" term="%22DIFFUSION+magnetic+resonance+imaging%22">DIFFUSION magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22LIVER+cancer%22">LIVER cancer</searchLink><br /><searchLink fieldCode="DE" term="%22DIAGNOSTIC+services%22">DIAGNOSTIC services</searchLink><br /><searchLink fieldCode="DE" term="%22CHOLANGIOCARCINOMA%22">CHOLANGIOCARCINOMA</searchLink><br /><searchLink fieldCode="DE" term="%22HEPATOCELLULAR+carcinoma%22">HEPATOCELLULAR carcinoma</searchLink><br /><searchLink fieldCode="DE" term="%22PATIENT+care%22">PATIENT care</searchLink><br /><searchLink fieldCode="DE" term="%22DIFFUSION+measurements%22">DIFFUSION measurements</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Purpose: To quantitatively assess the diagnostic value of DWI and ADC mapping in distinguishing liver metastases from primary hepatic malignancies (hepatocellular carcinoma and cholangiocarcinoma). Methods: DW-MRI data from patients with biopsy-proven malignant liver lesions were retrospectively analyzed. ADC values of metastatic lesions were compared to those of HCC and cholangiocarcinoma using t-tests and ROC analysis. Results: Mean ADC of metastases (0.81±0.19×10−3 mm2/s0.81±0.19×10−3mm2/s) was significantly lower than that of HCC (1.03±0.23×10−3 mm2/s1.03±0.23×10−3mm2/s), p=0.01. ROC analysis produced an AUC of 0.83 and an optimal cutoff of 0.90×10−3 mm2/s0.90×10−3mm2/s for identifying metastases Conclusion: DW-MRI ADC quantification is a practical adjunct for differentiating metastatic lesions from primary hepatic cancers, supporting more precise patient management. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label:
  Group: Ab
  Data: <i>Copyright of European Journal of Cardiovascular Medicine is the property of Healthcare Bulletin and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 10
        StartPage: 47
    Subjects:
      – SubjectFull: LIVER metastasis
        Type: general
      – SubjectFull: DIFFUSION magnetic resonance imaging
        Type: general
      – SubjectFull: LIVER cancer
        Type: general
      – SubjectFull: DIAGNOSTIC services
        Type: general
      – SubjectFull: CHOLANGIOCARCINOMA
        Type: general
      – SubjectFull: HEPATOCELLULAR carcinoma
        Type: general
      – SubjectFull: PATIENT care
        Type: general
      – SubjectFull: DIFFUSION measurements
        Type: general
    Titles:
      – TitleFull: A study of Differentiation of Liver Metastases and Primary Hepatic Malignancies Using Diffusion-Weighted MRI and ADC Measurements in a tertiary hospital in Central India.
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          Name:
            NameFull: Tekam, Sharda
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            NameFull: Yerme, Pravin
      – PersonEntity:
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            NameFull: Gandhi, Pranay
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            – D: 01
              M: 11
              Text: Nov2025
              Type: published
              Y: 2025
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              Value: 15
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              Value: 11
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            – TitleFull: European Journal of Cardiovascular Medicine
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