Bibliographische Detailangaben
| Titel: |
Short-term clinical and technical outcomes of a modified Zenker's peroral endoscopic myotomy with mucosal flap incision. |
| Autoren: |
Almario, Jose Antonio, Mehta, Amit, Shrigiriwar, Apurva, Fayyaz, Farimah, El-Sherbiny, Mohamed, Essam, Karim, Haggag, Hany, Yousef, Kerolis, Abdallatef, Abeer A., Elkholy, Shaimaa, Canakis, Andrew, Kim, Raymond E., Yang, Dennis, Puga-Tejada, Miguel, Alcívar-Vásquez, Juan, Egas-Izquierdo, Maria, Del Valle, Raquel S., Cunto, Domenica, Baquerizo-Burgos, Jorge, Arevalo-Mora, Martha |
| Quelle: |
Endoscopy; 2025, Vol. 57 Issue 4, p348-353, 6p |
| Schlagwörter: |
DIVERTICULUM, ENDOSCOPIC surgery, HEALTH outcome assessment, SURGICAL flaps, TREATMENT effectiveness, ADVERSE health care events |
| Abstract: |
Background: Zenker's diverticulum peroral endoscopic myotomy (Z-POEM) is an effective treatment for symptomatic Zenker's diverticulum. A modification to Z-POEM involves mucosal flap incision (MFI). We describe the technical and clinical success of patients who underwent Z-POEM with MFI. Methods: We included patients who underwent Z-POEM with MFI for Zenker's diverticulum at eight international centers. The primary outcome was the rate of clinical success, assessed by post-procedure Kothari–Haber symptom score (KHSS) without re-treatment. Secondary outcomes included technical success, serious adverse events, and clinical recurrence with need for re-treatment. Results: 36 patients (age 69 [SD 9] years; 69% male) underwent Z-POEM with MFI for symptomatic Zenker's diverticulum. Mean diverticulum size was 3.2 (SD 1.4) cm. Clinical success was achieved in 35 patients (97%). Median baseline KHSS was 6 and median post-procedure KHSS was 0 (P < 0.001). Technical success was achieved in all cases. Mean procedure time was 57 (SD 34) minutes and median follow-up time was 196 days (interquartile range 39–499). There was one adverse event (3%), which was treated endoscopically. Conclusion: Z-POEM with MFI had high rates of technical and clinical success. Prospective evaluation is needed to further validate this technique in patients with a large Zenker's diverticulum. [ABSTRACT FROM AUTHOR] |
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| Datenbank: |
Complementary Index |
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