The LIDPAD Mouse Model Captures the Multisystem Interactions and Extrahepatic Complications in MASLD (Adv. Sci. 35/2024).

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Název: The LIDPAD Mouse Model Captures the Multisystem Interactions and Extrahepatic Complications in MASLD (Adv. Sci. 35/2024).
Autoři: Low, Zun Siong, Chua, Damien, Cheng, Hong Sheng, Tee, Rachel, Tan, Wei Ren, Ball, Christopher, Sahib, Norliza Binte Esmail, Ng, Ser Sue, Qu, Jing, Liu, Yingzi, Hong, Haiyu, Cai, Chaonong, Rao, Nandini Chilagondanahalli Lakshmi, Wee, Aileen, Muthiah, Mark Dhinesh, Bichler, Zoë, Mickelson, Barbara, Kong, Mei Suen, Tay, Vanessa Shiyun, Yan, Zhuang
Zdroj: Advanced Science; 9/18/2024, Vol. 11 Issue 35, p1-1, 1p
Témata: LIVER diseases, METABOLIC syndrome, LABORATORY mice, ANIMAL disease models, DYSBIOSIS
Abstrakt: The article titled "The LIDPAD Mouse Model Captures the Multisystem Interactions and Extrahepatic Complications in MASLD" discusses a new mouse model called LIDPAD that accurately replicates metabolic dysfunction-associated steatotic liver disease (MASLD) in humans. The model incorporates factors such as metabolic syndrome, gut dysbiosis, multiorgan dysfunction, and neurobehavioral anomalies. The study highlights the close relevancy of the LIDPAD model to human MASLD, making it a valuable tool for further research in liver disease. The authors of the article are Nguan Soon Tan and Walter Wahli, among others. [Extracted from the article]
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Databáze: Complementary Index
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Abstrakt:The article titled "The LIDPAD Mouse Model Captures the Multisystem Interactions and Extrahepatic Complications in MASLD" discusses a new mouse model called LIDPAD that accurately replicates metabolic dysfunction-associated steatotic liver disease (MASLD) in humans. The model incorporates factors such as metabolic syndrome, gut dysbiosis, multiorgan dysfunction, and neurobehavioral anomalies. The study highlights the close relevancy of the LIDPAD model to human MASLD, making it a valuable tool for further research in liver disease. The authors of the article are Nguan Soon Tan and Walter Wahli, among others. [Extracted from the article]
ISSN:21983844
DOI:10.1002/advs.202470214