Inconsistent Condom Use and Reasons for Non-Use in the Era of HIV Pre-Exposure Prophylaxis Among German Men Who Have Sex with Men.

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Titel: Inconsistent Condom Use and Reasons for Non-Use in the Era of HIV Pre-Exposure Prophylaxis Among German Men Who Have Sex with Men.
Autoren: Moreland S; U.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Bethesda, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, Maryland, USA., Vyas KJ; U.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Bethesda, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, Maryland, USA., Jessen H; Private Practice Jessen2 + Kollegen, Berlin, Germany., Esser S; Institute for the Research on HIV and AIDS-associated Diseases, University of Duisburg-Essen, Essen, Germany.; HPSTD clinic, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Duff E; U.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Bethesda, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, Maryland, USA., Broach E; U.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Bethesda, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, Maryland, USA., Dorsey-Spitz J; U.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Bethesda, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, Maryland, USA., Frndak S; U.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Bethesda, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, Maryland, USA., Mebrahtu T; U.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Bethesda, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, Maryland, USA., Robb ML; U.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Bethesda, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, Maryland, USA., Streeck H; Institute of Virology, Medical Faculty, University of Bonn, Bonn, Germany.; German Center for Infection Research, Partner Site Bonn-Cologne, Bonn, Germany., Crowell TA; U.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Bethesda, Maryland, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine Inc., Bethesda, Maryland, USA.
Körperschaften: RV464 Study Group
Quelle: AIDS patient care and STDs [AIDS Patient Care STDS] 2025 Dec; Vol. 39 (12), pp. 505-514. Date of Electronic Publication: 2025 Nov 20.
Publikationsart: Journal Article
Sprache: English
Info zur Zeitschrift: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 9607225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7449 (Electronic) Linking ISSN: 10872914 NLM ISO Abbreviation: AIDS Patient Care STDS Subsets: MEDLINE
Imprint Name(s): Original Publication: Larchmont, NY : Mary Ann Liebert, Inc., c1996-
MeSH-Schlagworte: Homosexuality, Male*/statistics & numerical data , Homosexuality, Male*/psychology , Pre-Exposure Prophylaxis* , HIV Infections*/prevention & control , HIV Infections*/epidemiology , Condoms*/statistics & numerical data, Humans ; Male ; Germany/epidemiology ; Adult ; Surveys and Questionnaires ; Sexual Partners ; Sexual Behavior/statistics & numerical data ; Middle Aged ; Young Adult ; Prevalence ; Adolescent ; Safe Sex/statistics & numerical data
Abstract: Pre-exposure prophylaxis (PrEP) has shifted the paradigm of condom use and perceived risks for HIV and sexually transmitted infections (STIs) among men who have sex with men (MSM). We identified factors associated with inconsistent condom use and reasons for non-use among German MSM, with and without HIV, from two clinics in Germany between 2018 and 2024. Participants completed a questionnaire by computer-assisted self-interview every 6 months for up to 24 months. Multivariable robust Poisson regression models were fitted to estimate adjusted prevalence ratios (aPRs) and 95% confidence intervals (CIs) for the associations between factors of interest and inconsistent condom use and reasons for non-use. Inconsistent condom use was reported by 81% and 66% of 122 MSM during insertive and receptive anal sex, respectively. Inconsistent condom use was associated with (aPR [95% CI]) age >30 years (insertive: 31-40, 1.34 [1.13, 1.59]; ≥41, 1.27 [1.02, 1.58]), living without HIV (insertive: 1.28 [1.11, 1.47]; receptive: 1.32 [1.17, 1.49]), sex under the influence of drugs (insertive: 1.20 [1.04, 1.38]; receptive: 1.16 [1.03, 1.31]), and not worrying about STIs (insertive: 1.20 [1.06, 1.36]). Living with HIV, preference for condomless sex, and partner's HIV suppression were the most frequent reasons for non-use among participants with HIV. Using PrEP, preference for condomless sex, and partner's HIV status were the most frequent reasons for non-use among participants without HIV. Novel interventions tailored to specific high-risk subgroups, adjusted to address reasons for non-use, and adapted to mitigate risk compensation among MSM using PrEP are needed.
Contributed Indexing: Keywords: Germany; HIV; condoms; men who have sex with men; pre-exposure prophylaxis; sexually transmitted infections
Entry Date(s): Date Created: 20251120 Date Completed: 20251204 Latest Revision: 20251204
Update Code: 20251204
DOI: 10.1177/10872914251394785
PMID: 41265884
Datenbank: MEDLINE
Beschreibung
Abstract:Pre-exposure prophylaxis (PrEP) has shifted the paradigm of condom use and perceived risks for HIV and sexually transmitted infections (STIs) among men who have sex with men (MSM). We identified factors associated with inconsistent condom use and reasons for non-use among German MSM, with and without HIV, from two clinics in Germany between 2018 and 2024. Participants completed a questionnaire by computer-assisted self-interview every 6 months for up to 24 months. Multivariable robust Poisson regression models were fitted to estimate adjusted prevalence ratios (aPRs) and 95% confidence intervals (CIs) for the associations between factors of interest and inconsistent condom use and reasons for non-use. Inconsistent condom use was reported by 81% and 66% of 122 MSM during insertive and receptive anal sex, respectively. Inconsistent condom use was associated with (aPR [95% CI]) age >30 years (insertive: 31-40, 1.34 [1.13, 1.59]; ≥41, 1.27 [1.02, 1.58]), living without HIV (insertive: 1.28 [1.11, 1.47]; receptive: 1.32 [1.17, 1.49]), sex under the influence of drugs (insertive: 1.20 [1.04, 1.38]; receptive: 1.16 [1.03, 1.31]), and not worrying about STIs (insertive: 1.20 [1.06, 1.36]). Living with HIV, preference for condomless sex, and partner's HIV suppression were the most frequent reasons for non-use among participants with HIV. Using PrEP, preference for condomless sex, and partner's HIV status were the most frequent reasons for non-use among participants without HIV. Novel interventions tailored to specific high-risk subgroups, adjusted to address reasons for non-use, and adapted to mitigate risk compensation among MSM using PrEP are needed.
ISSN:1557-7449
DOI:10.1177/10872914251394785