Knowledge of the human papilloma virus and acceptance of its vaccine among male and female young adults in Jeddah, Saudi Arabia: A cross-sectional study.
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| Title: | Knowledge of the human papilloma virus and acceptance of its vaccine among male and female young adults in Jeddah, Saudi Arabia: A cross-sectional study. |
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| Authors: | Alghamdi R; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Alghamdi M; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Farsi N; Department of Dental Public Health, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia., Alyafi M; Department of Obstetrics and Gynecology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Alaidaroos S; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Almuwalad N; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Alsaeedi R; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Alshobaki K; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Aljabri R; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Aljadani R; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Bajafar R; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Aljuhani J; Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Merdad N; Psychology Department, Effat University, Jeddah, Saudi Arabia., Merdad R; Department of Community Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia. |
| Source: | Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2025 Dec; Vol. 21 (1), pp. 2583609. Date of Electronic Publication: 2025 Nov 17. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101572652 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2164-554X (Electronic) Linking ISSN: 21645515 NLM ISO Abbreviation: Hum Vaccin Immunother Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2015- : Philadelphia, PA : Taylor & Francis Original Publication: Austin, Tex. : Landes Bioscience |
| MeSH Terms: | Papillomavirus Vaccines*/administration & dosage , Health Knowledge, Attitudes, Practice* , Papillomavirus Infections*/prevention & control , Patient Acceptance of Health Care*/statistics & numerical data , Vaccination*/psychology , Vaccination*/statistics & numerical data, Humans ; Cross-Sectional Studies ; Saudi Arabia/epidemiology ; Female ; Male ; Young Adult ; Surveys and Questionnaires ; Students/psychology ; Students/statistics & numerical data ; Adult ; Uterine Cervical Neoplasms/prevention & control ; Uterine Cervical Neoplasms/virology ; Universities ; Adolescent ; Papillomaviridae/immunology ; COVID-19/prevention & control ; Vaccination Hesitancy/statistics & numerical data ; Human Papillomavirus Viruses |
| Abstract: | This study assessed university students' awareness and knowledge of human papillomavirus (HPV) and its vaccine and willingness to accept vaccination in Jeddah, Saudi Arabia, and identified factors associated with these outcomes. This cross-sectional study was conducted in Jeddah, Saudi Arabia. The study population included university-level male and female students. During the first term of the 2023-2024 academic year, eligible participants were sent an online questionnaire. The study variables included measures of sociodemographic factors, awareness and knowledge of HPV and its vaccine, and vaccine acceptance. We conducted descriptive analysis of awareness, good knowledge, and willingness to accept vaccination, and multivariable logistic regression analyses to determine predictors of these outcomes. The study included 400 participants with a mean age of 21.4years, predominantly female and of Saudi nationality (93%). Awareness of HPV infection was reported by 49.3% of participants, while 44% were aware of the HPV vaccine. Among those aware of HPV, 82.2% recognized its link to cervical cancer, but misconceptions about HPV exist. Only 3.8% of participants had been vaccinated for HPV, and 33.5% expressed willingness to accept the vaccine. Age (per 1year increment; OR: 1.42, 95% CI: 1.25 to 1.62, P < .001), mother's education level (doctorate or advanced degree vs. pre-high school; OR: 4.65, 95% CI: 1.51 to 14.32, P = .007), and COVID-19 vaccine (received 3 doses vs.<3; OR: 3.12, 95% CI: 1.78 to 5.45, P < .001) were significant predictors of better HPV awareness. Living abroad was significantly associated with higher HPV vaccination rates (OR: 4.39, 95% CI: 1.27 to 15.1, P = .02). Male students were less likely to be willing to accept vaccination than females (OR: 0.38, 95% CI: 0.20 to 0.72, P = .003). HPV awareness, knowledge, and vaccine acceptance remain low among Saudi university students, with very limited uptake. Older age, maternal education, and prior COVID-19 vaccination were key predictors of awareness, highlighting important targets for future public health strategies. Targeted university-based and digital interventions are urgently needed to address these gaps and support national and regional HPV vaccination strategies. Future research should evaluate the effectiveness of such interventions and explore cultural and gender-specific barriers to HPV vaccine uptake. |
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| Contributed Indexing: | Keywords: HPV vaccine; HPV vaccine acceptance; human papillomavirus (HPV) |
| Substance Nomenclature: | 0 (Papillomavirus Vaccines) |
| Entry Date(s): | Date Created: 20251117 Date Completed: 20251117 Latest Revision: 20251121 |
| Update Code: | 20251121 |
| PubMed Central ID: | PMC12629332 |
| DOI: | 10.1080/21645515.2025.2583609 |
| PMID: | 41247743 |
| Database: | MEDLINE |
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Nájsť tento článok vo Web of Science | Abstract: | This study assessed university students' awareness and knowledge of human papillomavirus (HPV) and its vaccine and willingness to accept vaccination in Jeddah, Saudi Arabia, and identified factors associated with these outcomes. This cross-sectional study was conducted in Jeddah, Saudi Arabia. The study population included university-level male and female students. During the first term of the 2023-2024 academic year, eligible participants were sent an online questionnaire. The study variables included measures of sociodemographic factors, awareness and knowledge of HPV and its vaccine, and vaccine acceptance. We conducted descriptive analysis of awareness, good knowledge, and willingness to accept vaccination, and multivariable logistic regression analyses to determine predictors of these outcomes. The study included 400 participants with a mean age of 21.4years, predominantly female and of Saudi nationality (93%). Awareness of HPV infection was reported by 49.3% of participants, while 44% were aware of the HPV vaccine. Among those aware of HPV, 82.2% recognized its link to cervical cancer, but misconceptions about HPV exist. Only 3.8% of participants had been vaccinated for HPV, and 33.5% expressed willingness to accept the vaccine. Age (per 1year increment; OR: 1.42, 95% CI: 1.25 to 1.62, P < .001), mother's education level (doctorate or advanced degree vs. pre-high school; OR: 4.65, 95% CI: 1.51 to 14.32, P = .007), and COVID-19 vaccine (received 3 doses vs.<3; OR: 3.12, 95% CI: 1.78 to 5.45, P < .001) were significant predictors of better HPV awareness. Living abroad was significantly associated with higher HPV vaccination rates (OR: 4.39, 95% CI: 1.27 to 15.1, P = .02). Male students were less likely to be willing to accept vaccination than females (OR: 0.38, 95% CI: 0.20 to 0.72, P = .003). HPV awareness, knowledge, and vaccine acceptance remain low among Saudi university students, with very limited uptake. Older age, maternal education, and prior COVID-19 vaccination were key predictors of awareness, highlighting important targets for future public health strategies. Targeted university-based and digital interventions are urgently needed to address these gaps and support national and regional HPV vaccination strategies. Future research should evaluate the effectiveness of such interventions and explore cultural and gender-specific barriers to HPV vaccine uptake. |
|---|---|
| ISSN: | 2164-554X |
| DOI: | 10.1080/21645515.2025.2583609 |