Utilizing Parent-Led, Internet-Delivered Cognitive Behavioral Therapy for Autistic Adolescents with Anxiety-Related Disorders: Preliminary Insights from the Development of the Learning to Understand and Navigate Anxiety for Adolescents Program.

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Title: Utilizing Parent-Led, Internet-Delivered Cognitive Behavioral Therapy for Autistic Adolescents with Anxiety-Related Disorders: Preliminary Insights from the Development of the Learning to Understand and Navigate Anxiety for Adolescents Program.
Authors: Onyeka OC; Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, 1977 Butler Boulevard, Suite 4-400, Houston, TX 77025, USA. Electronic address: ogechi.onyeka@bcm.edu., Riddle DB; Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, 1977 Butler Boulevard, Suite 4-400, Houston, TX 77025, USA., Tan SXL; Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, 1977 Butler Boulevard, Suite 4-400, Houston, TX 77025, USA., Guzick A; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, 3535 Market Street, 6th Floor, Philadelphia, PA 19104, USA., Storch EA; Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, 1977 Butler Boulevard, Suite 4-400, Houston, TX 77025, USA.
Source: The Psychiatric clinics of North America [Psychiatr Clin North Am] 2025 Dec; Vol. 48 (4), pp. 723-736. Date of Electronic Publication: 2025 Sep 15.
Publication Type: Journal Article; Review
Language: English
Journal Info: Publisher: W B Saunders Country of Publication: United States NLM ID: 7708110 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-3147 (Electronic) Linking ISSN: 0193953X NLM ISO Abbreviation: Psychiatr Clin North Am Subsets: MEDLINE
Imprint Name(s): Publication: Philadelphia Pa : W B Saunders
Original Publication: Philadelphia, Saunders.
MeSH Terms: Cognitive Behavioral Therapy*/methods , Anxiety Disorders*/therapy , Anxiety Disorders*/complications , Parents*/education , Autistic Disorder*/therapy , Autistic Disorder*/complications , Internet-Based Intervention*, Humans ; Adolescent ; Internet
Abstract: Competing Interests: Disclosure O.C. Onyeka receives research support from the National Institute of Mental Health, United States (3U01MH125062-03S2), the International OCD Foundation, and the Texas Child Mental Health Care Consortium. E.A. Storch reports receiving research funding to his institution from the REAM Foundation, United States, International OCD Foundation, United States, and the NIH, United States. He was a consultant for Brainsway and Biohaven Pharmaceuticals in the past 24 months. He owns stock less than $5000 in NView (for the distribution of the Y-BOCS and CY-BOCS). He receives book royalties from Elsevier, Wiley, Oxford, American Psychological Association, Guildford, Springer, Routledge, and Jessica Kingsley. Dr A. Guzick has received research support from the Texas Higher Education Coordinating Board, United States to develop the program described in this review. D.B. Riddle and S.X.L. Tan have no conflicts to disclose.
Autism affects 2% to 3% of youth, approximately half of whom experience a co-occurring anxiety disorder. Left untreated, anxiety symptoms show a worsening trajectory into adulthood and increase the functional impact of the core autism symptoms. Innovative treatment approaches such as Internet-CBT adapted for autistic youth demonstrate preliminary effectiveness in symptom reduction while overcoming barriers and increasing accessibility. Insights and considerations regarding the development of the Learning to Understand and Navigate Anxiety for Adolescents (LUNA-Adolescent) program are presented as a promising approach to treatment for autistic adolescents and their families.
(Copyright © 2025 Elsevier Inc. All rights reserved.)
Contributed Indexing: Keywords: Adolescents; Anxiety; Autism; CBT; Internet-CBT
Entry Date(s): Date Created: 20251105 Date Completed: 20251105 Latest Revision: 20251105
Update Code: 20251106
DOI: 10.1016/j.psc.2025.06.008
PMID: 41193067
Database: MEDLINE
Description
Abstract:Competing Interests: Disclosure O.C. Onyeka receives research support from the National Institute of Mental Health, United States (3U01MH125062-03S2), the International OCD Foundation, and the Texas Child Mental Health Care Consortium. E.A. Storch reports receiving research funding to his institution from the REAM Foundation, United States, International OCD Foundation, United States, and the NIH, United States. He was a consultant for Brainsway and Biohaven Pharmaceuticals in the past 24 months. He owns stock less than $5000 in NView (for the distribution of the Y-BOCS and CY-BOCS). He receives book royalties from Elsevier, Wiley, Oxford, American Psychological Association, Guildford, Springer, Routledge, and Jessica Kingsley. Dr A. Guzick has received research support from the Texas Higher Education Coordinating Board, United States to develop the program described in this review. D.B. Riddle and S.X.L. Tan have no conflicts to disclose.<br />Autism affects 2% to 3% of youth, approximately half of whom experience a co-occurring anxiety disorder. Left untreated, anxiety symptoms show a worsening trajectory into adulthood and increase the functional impact of the core autism symptoms. Innovative treatment approaches such as Internet-CBT adapted for autistic youth demonstrate preliminary effectiveness in symptom reduction while overcoming barriers and increasing accessibility. Insights and considerations regarding the development of the Learning to Understand and Navigate Anxiety for Adolescents (LUNA-Adolescent) program are presented as a promising approach to treatment for autistic adolescents and their families.<br /> (Copyright © 2025 Elsevier Inc. All rights reserved.)
ISSN:1558-3147
DOI:10.1016/j.psc.2025.06.008