Accelerometer-measured "weekend warrior" physical activity and incident cardiovascular disease in adults with type 2 diabetes mellitus or prediabetes: A prospective cohort study.
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| Titel: | Accelerometer-measured "weekend warrior" physical activity and incident cardiovascular disease in adults with type 2 diabetes mellitus or prediabetes: A prospective cohort study. |
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| Autoren: | Yang H; Department of Epidemiology, School of Public Health, Children's Hospital Affiliated to Shandong University (Jinan Children's Hospital), Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China., Qiao Y; Department of Epidemiology, School of Public Health, Children's Hospital Affiliated to Shandong University (Jinan Children's Hospital), Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China., Lin R; Department of Biostatistics, School of Public Health, and The Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai, China., Yu Y; Department of Biostatistics, School of Public Health, and The Key Laboratory of Public Health Safety of Ministry of Education, Fudan University, Shanghai, China; Shanghai Institute of Infectious Disease and Biosecurity, Shanghai, China., Zhao M; Department of Nutrition and Food Hygiene, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China., Magnussen CG; Baker Heart and Diabetes Institute, Melbourne, VIC, Australia; Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland; Alliance for Research in Exercise, Nutrition and Activity (ARENA), University of South Australia, Adelaide, Australia., Xi B; Department of Epidemiology, School of Public Health, Children's Hospital Affiliated to Shandong University (Jinan Children's Hospital), Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China. Electronic address: xxxiyyy2024@163.com. |
| Quelle: | Diabetes research and clinical practice [Diabetes Res Clin Pract] 2025 Nov; Vol. 229, pp. 112948. Date of Electronic Publication: 2025 Oct 15. |
| Publikationsart: | Journal Article |
| Sprache: | English |
| Info zur Zeitschrift: | Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8508335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8227 (Electronic) Linking ISSN: 01688227 NLM ISO Abbreviation: Diabetes Res Clin Pract Subsets: MEDLINE |
| Imprint Name(s): | Publication: 1993- : Limerick : Elsevier Scientific Publishers Original Publication: Amsterdam : Elsevier Science Publishers B.V., c1985- |
| MeSH-Schlagworte: | Diabetes Mellitus, Type 2*/complications , Diabetes Mellitus, Type 2*/epidemiology , Diabetes Mellitus, Type 2*/physiopathology , Prediabetic State*/epidemiology , Prediabetic State*/complications , Prediabetic State*/physiopathology , Exercise*/physiology , Cardiovascular Diseases*/epidemiology, Humans ; Middle Aged ; Female ; Male ; Accelerometry ; Adult ; Prospective Studies ; Aged ; Incidence |
| Abstract: | Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Background: Adherence to guideline-recommended optimal dose (≥150 min/week of moderate-to-vigorous physical activity [MVPA]) has been associated with reduced risk of cardiovascular disease (CVD) in adults with type 2 diabetes mellitus (T2DM) or prediabetes. However, the influence of different PA patterns, such as concentrated versus evenly distributed activity, on this risk remains unclear. We aimed to examine the associations of accelerometer-measured "weekend warrior" (WW) and active regular patterns with incident CVD in adults with T2DM or prediabetes. Methods: Using accelerometer data from 10,989 participants with T2DM or prediabetes (aged 43-78 years) from the UK Biobank, we categorized participants into three PA patterns: active WW pattern (guideline-recommended optimal dose with ≥ 50 % of MVPA concentrated over 1-2 days/week), active regular pattern (guideline-recommended optimal dose with ≥ 50 % of MVPA spread across > 2 days/week), and the inactive pattern (<150 min/week of MVPA). The primary outcomes, including overall CVD, myocardial infarction (MI), atrial fibrillation (AF), heart failure (HF), and stroke, were obtained from hospital and death records. Cox proportional hazards regression was used for the analyses, with results presented as hazard ratios (HRs) with 95 % confidence intervals (CIs). Results: Over a median follow-up of 7.86 years, 1,128 CVD cases were identified. Compared to inactive individuals, the active WW group had a lower risk of overall CVD, MI, AF, and HF, with HRs and 95 % CIs of 0.72 (0.63-0.83), 0.66 (0.51-0.85), 0.70 (0.58-0.85), and 0.66 (0.51-0.86), respectively. Similar risk reductions were observed in the active regular group (overall CVD: 0.75 [0.64-0.89], MI: 0.58 [0.42-0.80], AF: 0.85 [0.68-1.05], HF: 0.51 [0.36-0.72]). Conclusion: The active WW pattern, concentrating guideline-recommended MVPA into 1-2 days, was similar to the active regular pattern in reducing the risk of CVD in adults with T2DM or prediabetes. (Copyright © 2025 Elsevier B.V. All rights reserved.) |
| Contributed Indexing: | Keywords: Accelerometry; Cardiovascular diseases; Diabetes mellitus; Exercise patterns; Physical activity; Prediabetic state; Weekend warrior |
| Entry Date(s): | Date Created: 20251017 Date Completed: 20251030 Latest Revision: 20251030 |
| Update Code: | 20251031 |
| DOI: | 10.1016/j.diabres.2025.112948 |
| PMID: | 41106504 |
| Datenbank: | MEDLINE |
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Nájsť tento článok vo Web of Science | Abstract: | Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br />Background: Adherence to guideline-recommended optimal dose (≥150 min/week of moderate-to-vigorous physical activity [MVPA]) has been associated with reduced risk of cardiovascular disease (CVD) in adults with type 2 diabetes mellitus (T2DM) or prediabetes. However, the influence of different PA patterns, such as concentrated versus evenly distributed activity, on this risk remains unclear. We aimed to examine the associations of accelerometer-measured "weekend warrior" (WW) and active regular patterns with incident CVD in adults with T2DM or prediabetes.<br />Methods: Using accelerometer data from 10,989 participants with T2DM or prediabetes (aged 43-78 years) from the UK Biobank, we categorized participants into three PA patterns: active WW pattern (guideline-recommended optimal dose with ≥ 50 % of MVPA concentrated over 1-2 days/week), active regular pattern (guideline-recommended optimal dose with ≥ 50 % of MVPA spread across > 2 days/week), and the inactive pattern (<150 min/week of MVPA). The primary outcomes, including overall CVD, myocardial infarction (MI), atrial fibrillation (AF), heart failure (HF), and stroke, were obtained from hospital and death records. Cox proportional hazards regression was used for the analyses, with results presented as hazard ratios (HRs) with 95 % confidence intervals (CIs).<br />Results: Over a median follow-up of 7.86 years, 1,128 CVD cases were identified. Compared to inactive individuals, the active WW group had a lower risk of overall CVD, MI, AF, and HF, with HRs and 95 % CIs of 0.72 (0.63-0.83), 0.66 (0.51-0.85), 0.70 (0.58-0.85), and 0.66 (0.51-0.86), respectively. Similar risk reductions were observed in the active regular group (overall CVD: 0.75 [0.64-0.89], MI: 0.58 [0.42-0.80], AF: 0.85 [0.68-1.05], HF: 0.51 [0.36-0.72]).<br />Conclusion: The active WW pattern, concentrating guideline-recommended MVPA into 1-2 days, was similar to the active regular pattern in reducing the risk of CVD in adults with T2DM or prediabetes.<br /> (Copyright © 2025 Elsevier B.V. All rights reserved.) |
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| ISSN: | 1872-8227 |
| DOI: | 10.1016/j.diabres.2025.112948 |