Applying the Human-Centered Innovation Biodesign Framework to the Development and Piloting of a Program to Mitigate Risk for Cognitive Decline Among Historically Underrepresented Individuals: Case Study.
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| Názov: | Applying the Human-Centered Innovation Biodesign Framework to the Development and Piloting of a Program to Mitigate Risk for Cognitive Decline Among Historically Underrepresented Individuals: Case Study. |
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| Autori: | Lassell R; Department of Health and Wellness Design, School of Public Health, Indiana University, Bloomington, IN, United States.; Regenstrief Institute, Indiana University Center for Aging Research, Indianapolis, IN, United States., Metaxas A; Department of Chemistry, Princeton University, Princeton, NJ, United States., Wang K; Albert Einstein College of Medicine, Bronx, NY, United States., Hantgan S; Michigan Medicine Department of Computational Medicine and Bioinformatics, University of Michigan School of Literature, Science, and the Arts, University of Michigan School of Information, Ann Arbor, MI, United States., Gottipati P; Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States., Zwerling S; College of Human Ecology and majoring in Human Development, Cornell University, Ithaca, NY, United States., Pena T; Department of Health and Wellness Design, School of Public Health, Indiana University, Bloomington, IN, United States., Pollak C; Department of Neurology, Stony Brook Medicine, Long Island, NY, United States., Gitlin L; College of Nursing and Health Professions, Drexel University, Philadelphia, PA, United States., Jariwala S; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, United States.; Division of Allergy/Immunology, Albert Einstein College of Medicine, Bronx, NY, United States. |
| Zdroj: | JMIR formative research [JMIR Form Res] 2025 Oct 15; Vol. 9, pp. e64930. Date of Electronic Publication: 2025 Oct 15. |
| Spôsob vydávania: | Journal Article |
| Jazyk: | English |
| Informácie o časopise: | Publisher: JMIR Publications Country of Publication: Canada NLM ID: 101726394 Publication Model: Electronic Cited Medium: Internet ISSN: 2561-326X (Electronic) Linking ISSN: 2561326X NLM ISO Abbreviation: JMIR Form Res Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Toronto, ON, Canada : JMIR Publications, [2017]- |
| Výrazy zo slovníka MeSH: | Cognitive Dysfunction*/prevention & control , Program Development*/methods , Exercise* , User-Centered Design*, Humans ; Pilot Projects ; Male ; Female ; Aged ; Dementia/prevention & control ; Risk Factors ; Needs Assessment |
| Abstrakt: | Background: Physical inactivity is a modifiable risk factor for dementia. Past physical activity interventions often overlook the voices of the end user in the design process, particularly minoritized groups living with dementia or memory challenges. To develop physical activity interventions, we use the principles of human-centered design. Objective: We applied human-centered design using the innovation biodesign framework to develop a physical activity intervention, Nurturing Aging Through Uplifting Activities in a Restorative Environment (NATURE) program for minoritized individuals as a use case. Methods: The innovation biodesign framework has three domains: (1) problem space, (2) invention, and (3) solution space. Each domain includes several activities. The problem space involves a needs assessment, needs screening, evidence-based literature review, review of existing models of programs, and iterative feedback from partners, leading to an invention. The solution space encompasses the implementation and validation of the invention and outcomes. We applied this framework in 3 steps: (1) identifying the problem: we used data points from multiple sources to identify needs and mapped them onto the problem space. These sources included reviews of the literature to identify existing interventions, findings from other nature programs to surmise gaps, and focus groups to iteratively identify unmet needs. (2) Designing the invention: we developed NATURE with Hispanic or Latino people with memory challenges and identified their preferred outcomes. (3) Mapping the pilot study. We added the study protocol and planned outcomes to the solution space. Results: In step 1, three evidence-based programs guided the development of NATURE to address physical inactivity and related risks of decreased well-being and dementia. We received 50 referrals for focus group participants, 22 were eligible and completed consent, and 21 (n=6 Hispanic or Latino people with memory challenges and care partners, n=8 outdoor professionals, and n=7 health care providers) participants completed the focus groups. We received feedback from participants on local nature activities, program frequency, duration, and delivery mode, a referral pathway, and outcomes using 5 focus groups and 2 interviews. In step 2, the 12-week NATURE program was developed to promote an active lifestyle and well-being, using nature activities that a person enjoys. NATURE accounts for a person's preferences, needs, and daily situation and includes 4-6 sessions with 2 phone check-ins. Preferred outcomes were well-being, sleep, and social connections. In step 3, we mapped the plan to pilot NATURE using activity tracker technology to measure sleep, heart rate, and activity (well-being), and validated questionnaires. Conclusions: The framework provided a systematic approach for mapping the development of NATURE to address the needs of Hispanic or Latino people with memory challenges, using human-centered design principles. Application of the framework can be a helpful tool to map the development of other interventions for minoritized populations. Trial Registration: ClinicalTrials.gov NCT06403345; https://clinicaltrials.gov/study/NCT06403345. (©Rebecca Lassell, Ada Metaxas, Katherine Wang, Sara Hantgan, Prabhat Gottipati, Sarah Zwerling, Triana Pena, Chava Pollak, Laura Gitlin, Sunit Jariwala. Originally published in JMIR Formative Research (https://formative.jmir.org), 15.10.2025.) |
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| Contributed Indexing: | Keywords: Alzheimer’s; Alzheimer’s disease; biodesign; cognition; cognitive; cognitive decline; dementia; gaps; human-centered; human-centered design; innovation; lifestyle intervention; medical innovation; nature-based; physical activity; user-centered design |
| Molecular Sequence: | ClinicalTrials.gov NCT06403345 |
| Entry Date(s): | Date Created: 20251015 Date Completed: 20251015 Latest Revision: 20251120 |
| Update Code: | 20251121 |
| PubMed Central ID: | PMC12572745 |
| DOI: | 10.2196/64930 |
| PMID: | 41092385 |
| Databáza: | MEDLINE |
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Nájsť tento článok vo Web of Science | Abstrakt: | Background: Physical inactivity is a modifiable risk factor for dementia. Past physical activity interventions often overlook the voices of the end user in the design process, particularly minoritized groups living with dementia or memory challenges. To develop physical activity interventions, we use the principles of human-centered design.<br />Objective: We applied human-centered design using the innovation biodesign framework to develop a physical activity intervention, Nurturing Aging Through Uplifting Activities in a Restorative Environment (NATURE) program for minoritized individuals as a use case.<br />Methods: The innovation biodesign framework has three domains: (1) problem space, (2) invention, and (3) solution space. Each domain includes several activities. The problem space involves a needs assessment, needs screening, evidence-based literature review, review of existing models of programs, and iterative feedback from partners, leading to an invention. The solution space encompasses the implementation and validation of the invention and outcomes. We applied this framework in 3 steps: (1) identifying the problem: we used data points from multiple sources to identify needs and mapped them onto the problem space. These sources included reviews of the literature to identify existing interventions, findings from other nature programs to surmise gaps, and focus groups to iteratively identify unmet needs. (2) Designing the invention: we developed NATURE with Hispanic or Latino people with memory challenges and identified their preferred outcomes. (3) Mapping the pilot study. We added the study protocol and planned outcomes to the solution space.<br />Results: In step 1, three evidence-based programs guided the development of NATURE to address physical inactivity and related risks of decreased well-being and dementia. We received 50 referrals for focus group participants, 22 were eligible and completed consent, and 21 (n=6 Hispanic or Latino people with memory challenges and care partners, n=8 outdoor professionals, and n=7 health care providers) participants completed the focus groups. We received feedback from participants on local nature activities, program frequency, duration, and delivery mode, a referral pathway, and outcomes using 5 focus groups and 2 interviews. In step 2, the 12-week NATURE program was developed to promote an active lifestyle and well-being, using nature activities that a person enjoys. NATURE accounts for a person's preferences, needs, and daily situation and includes 4-6 sessions with 2 phone check-ins. Preferred outcomes were well-being, sleep, and social connections. In step 3, we mapped the plan to pilot NATURE using activity tracker technology to measure sleep, heart rate, and activity (well-being), and validated questionnaires.<br />Conclusions: The framework provided a systematic approach for mapping the development of NATURE to address the needs of Hispanic or Latino people with memory challenges, using human-centered design principles. Application of the framework can be a helpful tool to map the development of other interventions for minoritized populations.<br />Trial Registration: ClinicalTrials.gov NCT06403345; https://clinicaltrials.gov/study/NCT06403345.<br /> (©Rebecca Lassell, Ada Metaxas, Katherine Wang, Sara Hantgan, Prabhat Gottipati, Sarah Zwerling, Triana Pena, Chava Pollak, Laura Gitlin, Sunit Jariwala. Originally published in JMIR Formative Research (https://formative.jmir.org), 15.10.2025.) |
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| ISSN: | 2561-326X |
| DOI: | 10.2196/64930 |