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Priority research questions in microbiome-integrated urban design.

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Názov: Priority research questions in microbiome-integrated urban design.
Autori: Beckett R; The Bartlett School of Architecture, University College London, London, United Kingdom., Archer L; Department of Plant Sciences, University of Cambridge, Cambridge, England, United Kingdom., Barrable A; Division of Psychology, Sociology and Education, Queen Margaret University, Edinburgh, Scotland, United Kingdom., Bogdan-Margineanu M; Cancer Neuroscience Laboratory, The Francis Crick Institute, London, United Kingdom.; Faculty of Medicine, 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania., Bradley S; Groundwork, London, United Kingdom., Hawes S; College Green, Bristol City Council, The Council House, Bristol, United Kingdom., Herr C; School of Design, SUSTech (Southern University of Science and Technology), Shenzhen, China., Housen M; Institute for Advanced Architecture of Catalonia, Carrer de Pujades, Barcelona, Spain., Lacatusu A; Bio-ID Lab, The Bartlett School of Architecture, University College London, London, United Kingdom., Laitinen O; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Roslund M; Natural Resources Institute Finland (Luke), Helsinki, Finland., Rumble H; Centre for Sustainable Planning and Environments, University of the West of England (Bristol), Bristol, United Kingdom., Scott W; Department of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, United Kingdom., Sinkkonen A; Natural Resources Institute Finland (Luke), Turku, Finland., Sun X; State Key Laboratory of Regional and Urban Ecology, Ningbo Observation and Research Station, Fujian Key Laboratory of Watershed Ecology, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, China.; Zhejiang Key Laboratory of Urban Environmental Processes and Pollution Control, CASHaixi Industrial Technology Innovation Center in Beilun, Ningbo, China.; University of Chinese Academy of Sciences, Beijing, China., Robinson JM; College of Science and Engineering, Flinders University, Bedford Park, Australia.; The Aerobiome Innovation and Research Hub, Flinders University, Bedford Park, Australia.
Zdroj: MSphere [mSphere] 2025 Nov 25; Vol. 10 (11), pp. e0061925. Date of Electronic Publication: 2025 Oct 14.
Spôsob vydávania: Journal Article; Review
Jazyk: English
Informácie o časopise: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101674533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2379-5042 (Electronic) Linking ISSN: 23795042 NLM ISO Abbreviation: mSphere Subsets: MEDLINE
Imprint Name(s): Original Publication: Washington, DC : American Society for Microbiology, [2015]-
Výrazy zo slovníka MeSH: Microbiota* , City Planning* , Urban Health* , Research*, Humans ; Cities ; Probiotics ; Urbanization ; Ecosystem ; Sustainable Development
Abstrakt: Competing Interests: The authors declare no conflict of interest.
Urbanization is accelerating at an unprecedented pace, with 70% of the global population projected to live in cities by 2050. This shift presents significant challenges and opportunities for fostering sustainable urban ecosystems aligned with the United Nations Sustainable Development Goals. Microbiomes-the diverse communities of microorganisms that underpin ecosystem function-are increasingly recognized for their vital role in nutrient cycling, climate regulation, biodiversity support, and human well-being. However, their consideration and integration in urban design remain underexplored, often limited to disease mitigation. The emerging field of microbiome-integrated urban design seeks to leverage microbial activity to enhance urban health and resilience through a multispecies framework. To address critical gaps, the Probiotic Cities Working Group convened a global interdisciplinary workshop, engaging experts from ecology, architecture, urban planning, immunology, and social sciences. Using reverse brainstorming and thematic analysis, participants identified eight core themes and 40 priority research questions (via a modified Delphi technique). These themes span communication and policy, pollution prevention, interdisciplinary collaboration, experimental design, ethics, and public perception of microbiomes. A binomial concordance analysis revealed strong consensus on the top-ranked questions, which address urgent needs such as improving science communication, defining success metrics, and promoting evidence-based microbiome interventions. This paper discusses the top-ranked priority research questions and their broader implications for microbiome science, urban health, and sustainable development. By focusing on these priorities, researchers, policymakers, and practitioners can foster a transformative agenda to integrate microbiomes into urban design, advancing resilient and equitable cities for the future.
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Grant Information: 32361143523 National Natural Science Foundation of China; 2023YFF1304600 National Key Research and Development Program of China; 322GJHZ2022028FN International Partnership Program of Chinese Academy of Sciences
Contributed Indexing: Keywords: bioaugmented design; biodesign; biointegrated design; microbiome; urban ecology
Entry Date(s): Date Created: 20251014 Date Completed: 20251125 Latest Revision: 20251127
Update Code: 20251127
PubMed Central ID: PMC12645966
DOI: 10.1128/msphere.00619-25
PMID: 41085331
Databáza: MEDLINE
Popis
Abstrakt:Competing Interests: The authors declare no conflict of interest.<br />Urbanization is accelerating at an unprecedented pace, with 70% of the global population projected to live in cities by 2050. This shift presents significant challenges and opportunities for fostering sustainable urban ecosystems aligned with the United Nations Sustainable Development Goals. Microbiomes-the diverse communities of microorganisms that underpin ecosystem function-are increasingly recognized for their vital role in nutrient cycling, climate regulation, biodiversity support, and human well-being. However, their consideration and integration in urban design remain underexplored, often limited to disease mitigation. The emerging field of microbiome-integrated urban design seeks to leverage microbial activity to enhance urban health and resilience through a multispecies framework. To address critical gaps, the Probiotic Cities Working Group convened a global interdisciplinary workshop, engaging experts from ecology, architecture, urban planning, immunology, and social sciences. Using reverse brainstorming and thematic analysis, participants identified eight core themes and 40 priority research questions (via a modified Delphi technique). These themes span communication and policy, pollution prevention, interdisciplinary collaboration, experimental design, ethics, and public perception of microbiomes. A binomial concordance analysis revealed strong consensus on the top-ranked questions, which address urgent needs such as improving science communication, defining success metrics, and promoting evidence-based microbiome interventions. This paper discusses the top-ranked priority research questions and their broader implications for microbiome science, urban health, and sustainable development. By focusing on these priorities, researchers, policymakers, and practitioners can foster a transformative agenda to integrate microbiomes into urban design, advancing resilient and equitable cities for the future.
ISSN:2379-5042
DOI:10.1128/msphere.00619-25