Global strategies to achieve SDG 3.2 for ending preventable deaths of children under-five: A realist review.

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Bibliographic Details
Title: Global strategies to achieve SDG 3.2 for ending preventable deaths of children under-five: A realist review.
Authors: Qian W; Department of General Surgery, Royal North Shore Hospital. St Leonards, NSW, 2065, Australia; Faculty of Medicine and Health, The University of Sydney. Camperdown, NSW, 2050, Australia. Electronic address: william.qian@health.nsw.gov.au.
Source: Public health [Public Health] 2025 Nov; Vol. 248, pp. 105967. Date of Electronic Publication: 2025 Sep 24.
Publication Type: Journal Article; Systematic Review; Review
Language: English
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0376507 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5616 (Electronic) Linking ISSN: 00333506 NLM ISO Abbreviation: Public Health Subsets: MEDLINE
Imprint Name(s): Publication: 2003- : Amsterdam : Elsevier
Original Publication: London ; New York : Academic Press
MeSH Terms: Child Mortality*/trends , Global Health* , Sustainable Development* , Infant Mortality*/trends, Humans ; Child, Preschool ; Infant ; Infant, Newborn
Abstract: Objectives: At current trends, 59 countries are at risk of missing the sustainable development goal (SDG) target of bringing the under-five mortality rate to as low as 2.5 % per live birth by 2030. This article aims to identify effective global strategies for reducing under-five mortality and achieving SDG 3.2 targets.
Study Design: A realist synthesis method was used to systematically review the literature for evidence in accordance with the "Realist and MEta-narrative Evidence Syntheses: Evolving Standards" (RAMESES) publication standards. The context-mechanism-outcome (CMO) framework was applied to identify how global strategies function across settings.
Methods: Studies were identified through systematic searches of MEDLINE, Embase, and Cochrane databases from September 2000 to September 2024, scanning reference lists, and citation searching of key papers. Studies for inclusion described global strategies that contribute to ending preventable deaths in children under-five and achieving SDG 3.2 targets by 2030. Data were extracted using standardised forms and analysed for CMO configurations to identify, analyse, and produce an evidence-based framework of global strategies that contribute to ending preventable deaths in children under-five.
Results: Global strategies identified revolved around three core themes: leadership, health sector, and non-health sector factors. Key global strategic areas included increased governance, accountability for resources and results, community-based approaches, and prioritisation of interventions.
Conclusion: Multiple global strategies to reduce under-five mortality exist. This evidence-based synthesis of successful strategies, mapped using realist principles, provides a practical guide for policymakers worldwide to prioritise and adapt interventions across diverse country settings to accelerate progress towards achieving SDG 3.2.
(Copyright © 2025. Published by Elsevier Ltd.)
Contributed Indexing: Keywords: Children; Global strategies; Preventable death; SDG 3.2; Sustainable development goals; Under-five
Entry Date(s): Date Created: 20250925 Date Completed: 20251107 Latest Revision: 20251107
Update Code: 20251108
DOI: 10.1016/j.puhe.2025.105967
PMID: 40997514
Database: MEDLINE
Description
Abstract:Objectives: At current trends, 59 countries are at risk of missing the sustainable development goal (SDG) target of bringing the under-five mortality rate to as low as 2.5 % per live birth by 2030. This article aims to identify effective global strategies for reducing under-five mortality and achieving SDG 3.2 targets.<br />Study Design: A realist synthesis method was used to systematically review the literature for evidence in accordance with the "Realist and MEta-narrative Evidence Syntheses: Evolving Standards" (RAMESES) publication standards. The context-mechanism-outcome (CMO) framework was applied to identify how global strategies function across settings.<br />Methods: Studies were identified through systematic searches of MEDLINE, Embase, and Cochrane databases from September 2000 to September 2024, scanning reference lists, and citation searching of key papers. Studies for inclusion described global strategies that contribute to ending preventable deaths in children under-five and achieving SDG 3.2 targets by 2030. Data were extracted using standardised forms and analysed for CMO configurations to identify, analyse, and produce an evidence-based framework of global strategies that contribute to ending preventable deaths in children under-five.<br />Results: Global strategies identified revolved around three core themes: leadership, health sector, and non-health sector factors. Key global strategic areas included increased governance, accountability for resources and results, community-based approaches, and prioritisation of interventions.<br />Conclusion: Multiple global strategies to reduce under-five mortality exist. This evidence-based synthesis of successful strategies, mapped using realist principles, provides a practical guide for policymakers worldwide to prioritise and adapt interventions across diverse country settings to accelerate progress towards achieving SDG 3.2.<br /> (Copyright © 2025. Published by Elsevier Ltd.)
ISSN:1476-5616
DOI:10.1016/j.puhe.2025.105967