Schmallenberg virus exposure in camels and donkeys: Potential reservoirs for trans-border spread in the Nigeria-Sahel region.
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| Názov: | Schmallenberg virus exposure in camels and donkeys: Potential reservoirs for trans-border spread in the Nigeria-Sahel region. |
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| Autori: | Adikwu AA; Public Health and Tropical Medicine, College of Medicine and Dentistry, James Cook University, Townsville, QLD, Australia; Department of Public Health and Preventive Medicine, College of Veterinary Medicine, Joseph Sarwuan Tarka University, Makurdi, Nigeria; Centre for Tropical Biosecurity, James Cook University, Townsville, QLD, Australia. Electronic address: alex.adikwu@my.jcu.edu.au., Emeto TI; Public Health and Tropical Medicine, College of Medicine and Dentistry, James Cook University, Townsville, QLD, Australia; Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, QLD, Australia; World Health Organization Collaborating Centre for Vector-Borne and Neglected Tropical Diseases, College of Medicine and Dentistry, James Cook University, Townsville, QLD, Australia., Horwood PF; Veterinary Science, College of Sciences and Engineering, James Cook University, Townsville and Cairns, Townsville, QLD, Australia; Centre for Tropical Biosecurity, James Cook University, Townsville, QLD, Australia; Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, QLD, Australia., Owolodun OA; Biotechnology Division, National Veterinary Research Institute, Vom, Nigeria., Adamu AM; Veterinary Science, College of Sciences and Engineering, James Cook University, Townsville and Cairns, Townsville, QLD, Australia; Centre for Tropical Biosecurity, James Cook University, Townsville, QLD, Australia; Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, QLD, Australia., Ngbede EO; Institiute of Medical Microbiology and Hygiene, Saarland University, Homburg, Germany; Department of Veterinary Microbiology, College of Veterinary Medicine, Joseph Sarwuan Tarka University, Makurdi, Nigeria., Wungak YS; Viral Research Division, National Veterinary Research Institute, Vom, Nigeria., Ularamu HG; Viral Research Division, National Veterinary Research Institute, Vom, Nigeria., Adegboye OA; Public Health and Tropical Medicine, College of Medicine and Dentistry, James Cook University, Townsville, QLD, Australia; Centre for Tropical Biosecurity, James Cook University, Townsville, QLD, Australia; Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia. |
| Zdroj: | Veterinary journal (London, England : 1997) [Vet J] 2025 Dec; Vol. 314, pp. 106443. Date of Electronic Publication: 2025 Sep 17. |
| Spôsob vydávania: | Journal Article |
| Jazyk: | English |
| Informácie o časopise: | Publisher: Balliere Tindall Country of Publication: England NLM ID: 9706281 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2971 (Electronic) Linking ISSN: 10900233 NLM ISO Abbreviation: Vet J Subsets: MEDLINE |
| Imprint Name(s): | Publication: London : Balliere Tindall Original Publication: London : Ballière Tindall, c1997- |
| Výrazy zo slovníka MeSH: | Camelus* , Equidae* , Orthobunyavirus*/isolation & purification , Bunyaviridae Infections*/veterinary , Bunyaviridae Infections*/epidemiology , Bunyaviridae Infections*/virology , Bunyaviridae Infections*/transmission , Disease Reservoirs*/veterinary , Disease Reservoirs*/virology, Animals ; Seroepidemiologic Studies ; Female ; Nigeria/epidemiology ; Male ; Risk Factors ; Enzyme-Linked Immunosorbent Assay/veterinary ; Antibodies, Viral/blood |
| Abstrakt: | Livestock trade and altered migration patterns have influenced the spread of transboundary animal diseases (TADs). Schmallenberg virus (SBV), an emerging arboviral pathogen transmitted by biting midges, causes severe birth defects and abortions, transient fever, diarrhea, and reduced milk production in ruminants, exemplifying a global threat to domestic livestock populations. This study investigated the exposure of camels and donkeys to SBV and identified potential risk factors that may influence introduction and spread. A total of 460 serum samples from camels (n = 230) and donkeys (n = 230) were screened for SBV antibodies using a commercial enzyme-linked immunosorbent assay (ELISA), and data on potential risk factors were collected. The observed seroprevalence of SBV was 56.5 % in camels and 11.3 % in donkeys. Univariate analysis demonstrated a significantly higher seroprevalence in older camels (P = 0.008; odds ratio (OR) = 2.3; 95 % confidence interval (CI): 1.25-4.27) and donkeys (P = 0.004; OR = 3.41; 95 % CI: 1.48-7.97). Seropositivity was not significantly influenced by sex, management system, or mixed species rearing. Multivariable analysis revealed geographic clustering of infection risk, with significantly higher odds of seropositivity in camels from Zangon Daura (OR = 4.73; 95 % CI: 1.33-20.4) and donkeys from Sule Tankarkar (OR = 4.46; 95 % CI: 1.20-17.9). Our findings suggest that camels and donkeys are exposed to SBV and might serve as reservoirs and potential sources for spread within the region. Further molecular studies are recommended for a deeper understanding of SBV transmission dynamics. (Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved.) |
| Contributed Indexing: | Keywords: Camel; Disease; Donkey; Schmallenberg; Seroprevalence; Transboundary |
| Substance Nomenclature: | 0 (Antibodies, Viral) |
| Entry Date(s): | Date Created: 20250919 Date Completed: 20251204 Latest Revision: 20251204 |
| Update Code: | 20251205 |
| DOI: | 10.1016/j.tvjl.2025.106443 |
| PMID: | 40972912 |
| Databáza: | MEDLINE |
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Nájsť tento článok vo Web of Science | Abstrakt: | Livestock trade and altered migration patterns have influenced the spread of transboundary animal diseases (TADs). Schmallenberg virus (SBV), an emerging arboviral pathogen transmitted by biting midges, causes severe birth defects and abortions, transient fever, diarrhea, and reduced milk production in ruminants, exemplifying a global threat to domestic livestock populations. This study investigated the exposure of camels and donkeys to SBV and identified potential risk factors that may influence introduction and spread. A total of 460 serum samples from camels (n = 230) and donkeys (n = 230) were screened for SBV antibodies using a commercial enzyme-linked immunosorbent assay (ELISA), and data on potential risk factors were collected. The observed seroprevalence of SBV was 56.5 % in camels and 11.3 % in donkeys. Univariate analysis demonstrated a significantly higher seroprevalence in older camels (P = 0.008; odds ratio (OR) = 2.3; 95 % confidence interval (CI): 1.25-4.27) and donkeys (P = 0.004; OR = 3.41; 95 % CI: 1.48-7.97). Seropositivity was not significantly influenced by sex, management system, or mixed species rearing. Multivariable analysis revealed geographic clustering of infection risk, with significantly higher odds of seropositivity in camels from Zangon Daura (OR = 4.73; 95 % CI: 1.33-20.4) and donkeys from Sule Tankarkar (OR = 4.46; 95 % CI: 1.20-17.9). Our findings suggest that camels and donkeys are exposed to SBV and might serve as reservoirs and potential sources for spread within the region. Further molecular studies are recommended for a deeper understanding of SBV transmission dynamics.<br /> (Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved.) |
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| ISSN: | 1532-2971 |
| DOI: | 10.1016/j.tvjl.2025.106443 |