Glomerular Filtration Rate by Gamma Camera-Based Method: Interobserver Agreement at a Single Centre.
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| Title: | Glomerular Filtration Rate by Gamma Camera-Based Method: Interobserver Agreement at a Single Centre. |
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| Authors: | Sharoon R; Nuclear Medicine Centre, The Armed Forces Institute of Pathology, Rawalpindi, Pakistan., Dar ZS; Nuclear Medicine Centre, The Armed Forces Institute of Pathology, Rawalpindi, Pakistan., Atif M; Nuclear Cardiology Department, The Armed Forces Institute of Cardiology, Rawalpindi, Pakistan., Sikandar Z; Nuclear Medicine Centre, The Armed Forces Institute of Pathology, Rawalpindi, Pakistan., Fatima R; Nuclear Medicine Centre, The Armed Forces Institute of Pathology, Rawalpindi, Pakistan. |
| Source: | Journal of the College of Physicians and Surgeons--Pakistan : JCPSP [J Coll Physicians Surg Pak] 2025 Sep; Vol. 35 (9), pp. 1207-1209. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: College of Physicians and Surgeons Pakistan Country of Publication: Pakistan NLM ID: 9606447 Publication Model: Print Cited Medium: Internet ISSN: 1681-7168 (Electronic) Linking ISSN: 1022386X NLM ISO Abbreviation: J Coll Physicians Surg Pak Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Karachi : College of Physicians and Surgeons Pakistan, |
| MeSH Terms: | Glomerular Filtration Rate* , Gamma Cameras* , Radionuclide Imaging*/methods , Kidney*/diagnostic imaging, Humans ; Middle Aged ; Male ; Female ; Adult ; Cross-Sectional Studies ; Aged ; Observer Variation ; Child ; Prospective Studies ; Adolescent ; Technetium Tc 99m Pentetate ; Young Adult ; Radiopharmaceuticals ; Child, Preschool ; Pakistan |
| Abstract: | The objective of this study was to determine interobserver agreement (IOA) in the calculation of glomerular filtration rate (GFR) by the gamma camera-based method. It was a cross-sectional prospective study carried out at the Nuclear Medical Centre, the Armed Forces Institute of Pathology, Rawalpindi, Pakistan, from December 2021 to August 2022. A total of 52 patients with a median age of 47.20 years (range = 2-77 years) were included. All the patients underwent technetium-99m diethylene triamine pentaacetate (Tc-99m DTPA) renal scan following a standard protocol, and the scans were processed by the same group of three different observers. The patients were divided into four groups. The intraclass correlation coefficients (ICCs) for interobserver agreement in GFR estimation were as follows: Group 1 = 0.988 (95% CI: 0.971- 0.996), Group 2 = 0.997 (95% CI: 0.990 - 0.999), Group 3 = 0.985 (95% CI: 0.960 - 0.995), and Group 4 = 0.991 (95% CI, 0.976 - 0.996). The present study found excellent agreement among observers in estimating GFR using the gamma camera-based method. Key Words: Glomerular filtration rate, Interobserver variability, Intraclass correlation coefficient, Gamma camera imaging 99mTc-DTPA. |
| Substance Nomenclature: | VW78417PU1 (Technetium Tc 99m Pentetate) 0 (Radiopharmaceuticals) |
| Entry Date(s): | Date Created: 20250915 Date Completed: 20250916 Latest Revision: 20250916 |
| Update Code: | 20250917 |
| DOI: | 10.29271/jcpsp.2025.09.1207 |
| PMID: | 40948173 |
| Database: | MEDLINE |
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Nájsť tento článok vo Web of Science | Abstract: | The objective of this study was to determine interobserver agreement (IOA) in the calculation of glomerular filtration rate (GFR) by the gamma camera-based method. It was a cross-sectional prospective study carried out at the Nuclear Medical Centre, the Armed Forces Institute of Pathology, Rawalpindi, Pakistan, from December 2021 to August 2022. A total of 52 patients with a median age of 47.20 years (range = 2-77 years) were included. All the patients underwent technetium-99m diethylene triamine pentaacetate (Tc-99m DTPA) renal scan following a standard protocol, and the scans were processed by the same group of three different observers. The patients were divided into four groups. The intraclass correlation coefficients (ICCs) for interobserver agreement in GFR estimation were as follows: Group 1 = 0.988 (95% CI: 0.971- 0.996), Group 2 = 0.997 (95% CI: 0.990 - 0.999), Group 3 = 0.985 (95% CI: 0.960 - 0.995), and Group 4 = 0.991 (95% CI, 0.976 - 0.996). The present study found excellent agreement among observers in estimating GFR using the gamma camera-based method. Key Words: Glomerular filtration rate, Interobserver variability, Intraclass correlation coefficient, Gamma camera imaging 99mTc-DTPA. |
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| ISSN: | 1681-7168 |
| DOI: | 10.29271/jcpsp.2025.09.1207 |