View in EDS

Adapting to hypo-salinity: Molecular mechanisms in giant clams and symbionts with implications for coral reef resilience under climate change.

Saved in:
Bibliographic Details
Title: Adapting to hypo-salinity: Molecular mechanisms in giant clams and symbionts with implications for coral reef resilience under climate change.
Authors: Zhao Z; College of Animal Science and Technology, Guangxi University, Nanning 530004, China; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture (CAS), Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518120, China; Sanya National Marine Ecosystem Research Station, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Key Laboratory of Tropical Marine Biotechnology of Hainan Province, Sanya Institute of Ocean Eco-Environmental Engineering, Sanya 572000, China; Agro-Tech Extension Center of Guangdong Province, Guangzhou 510145, China; Daya Bay Marine Biology Research Station, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Shenzhen 518124, China., Duan X; College of Animal Science and Technology, Guangxi University, Nanning 530004, China; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture (CAS), Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518120, China; Sanya National Marine Ecosystem Research Station, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Key Laboratory of Tropical Marine Biotechnology of Hainan Province, Sanya Institute of Ocean Eco-Environmental Engineering, Sanya 572000, China; Agro-Tech Extension Center of Guangdong Province, Guangzhou 510145, China; Daya Bay Marine Biology Research Station, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Shenzhen 518124, China., Zhang T; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture (CAS), Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518120, China; Sanya National Marine Ecosystem Research Station, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Key Laboratory of Tropical Marine Biotechnology of Hainan Province, Sanya Institute of Ocean Eco-Environmental Engineering, Sanya 572000, China; Agro-Tech Extension Center of Guangdong Province, Guangzhou 510145, China; Daya Bay Marine Biology Research Station, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Shenzhen 518124, China., Bi S; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture (CAS), Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China., Noor Z; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture (CAS), Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518120, China; Sanya National Marine Ecosystem Research Station, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Key Laboratory of Tropical Marine Biotechnology of Hainan Province, Sanya Institute of Ocean Eco-Environmental Engineering, Sanya 572000, China; Agro-Tech Extension Center of Guangdong Province, Guangzhou 510145, China., Guo S; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture (CAS), Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518120, China; Sanya National Marine Ecosystem Research Station, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Key Laboratory of Tropical Marine Biotechnology of Hainan Province, Sanya Institute of Ocean Eco-Environmental Engineering, Sanya 572000, China., Wei Z; College of Animal Science and Technology, Guangxi University, Nanning 530004, China; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture (CAS), Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518120, China; Sanya National Marine Ecosystem Research Station, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Key Laboratory of Tropical Marine Biotechnology of Hainan Province, Sanya Institute of Ocean Eco-Environmental Engineering, Sanya 572000, China; Agro-Tech Extension Center of Guangdong Province, Guangzhou 510145, China; Daya Bay Marine Biology Research Station, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Shenzhen 518124, China., Zhang Y; College of Animal Science and Technology, Guangxi University, Nanning 530004, China; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture (CAS), Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518120, China; Sanya National Marine Ecosystem Research Station, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Key Laboratory of Tropical Marine Biotechnology of Hainan Province, Sanya Institute of Ocean Eco-Environmental Engineering, Sanya 572000, China; Agro-Tech Extension Center of Guangdong Province, Guangzhou 510145, China; Daya Bay Marine Biology Research Station, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Shenzhen 518124, China., Qin Y; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture (CAS), Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518120, China; Sanya National Marine Ecosystem Research Station, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Key Laboratory of Tropical Marine Biotechnology of Hainan Province, Sanya Institute of Ocean Eco-Environmental Engineering, Sanya 572000, China; Agro-Tech Extension Center of Guangdong Province, Guangzhou 510145, China; Daya Bay Marine Biology Research Station, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Shenzhen 518124, China., Ma H; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture (CAS), Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518120, China; Sanya National Marine Ecosystem Research Station, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Key Laboratory of Tropical Marine Biotechnology of Hainan Province, Sanya Institute of Ocean Eco-Environmental Engineering, Sanya 572000, China; Agro-Tech Extension Center of Guangdong Province, Guangzhou 510145, China; Daya Bay Marine Biology Research Station, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Shenzhen 518124, China., Pan Y; College of Animal Science and Technology, Guangxi University, Nanning 530004, China., Yu Z; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture (CAS), Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518120, China; Sanya National Marine Ecosystem Research Station, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Key Laboratory of Tropical Marine Biotechnology of Hainan Province, Sanya Institute of Ocean Eco-Environmental Engineering, Sanya 572000, China; Agro-Tech Extension Center of Guangdong Province, Guangzhou 510145, China; Daya Bay Marine Biology Research Station, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Shenzhen 518124, China., Li J; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture (CAS), Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518120, China; Sanya National Marine Ecosystem Research Station, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Key Laboratory of Tropical Marine Biotechnology of Hainan Province, Sanya Institute of Ocean Eco-Environmental Engineering, Sanya 572000, China; Agro-Tech Extension Center of Guangdong Province, Guangzhou 510145, China; Daya Bay Marine Biology Research Station, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Shenzhen 518124, China. Electronic address: jun.li@scsio.ac.cn., Zhang Y; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture (CAS), Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518120, China; Sanya National Marine Ecosystem Research Station, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Key Laboratory of Tropical Marine Biotechnology of Hainan Province, Sanya Institute of Ocean Eco-Environmental Engineering, Sanya 572000, China; Agro-Tech Extension Center of Guangdong Province, Guangzhou 510145, China; Daya Bay Marine Biology Research Station, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Shenzhen 518124, China. Electronic address: yhzhang@scsio.ac.cn.
Source: Environmental research [Environ Res] 2025 Nov 15; Vol. 285 (Pt 2), pp. 122385. Date of Electronic Publication: 2025 Jul 19.
Publication Type: Journal Article
Language: English
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0147621 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0953 (Electronic) Linking ISSN: 00139351 NLM ISO Abbreviation: Environ Res Subsets: MEDLINE
Imprint Name(s): Publication: <2000- > : Amsterdam : Elsevier
Original Publication: New York, Academic Press.
MeSH Terms: Coral Reefs* , Climate Change* , Bivalvia*/physiology , Salinity*, Animals ; Symbiosis ; Adaptation, Physiological
Abstract: Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Typhoon climates and extreme rainy seasons drive changes in seawater salinity and quality, threatening coral reef ecosystems. As key contributors to coral reef ecosystems, giant clams face major survival pressures from salinity fluctuations. Understanding their salinity adaptation and recovery strategies is thus critical for the long-term conservation and sustainable management of coral reefs. Here, we integrated physiological and meta-transcriptomic analyses to investigate responses of Tridacna crocea to hypo-saline conditions (20 ppt, 27 ppt) and subsequent recovery at 34 ppt. Hypo-salinity significantly reduced growth and survival, with only 69 % survival at 20 ppt, while elevated sodium-potassium pump (NKA) activity was observed, facilitating ion balance maintenance. Meta-transcriptomic analysis revealed downregulated genes related to antioxidants (GGT1), ABC transporters (ABCB11, ABCA12), and fatty acid metabolism (ACAA1), alongside upregulated genes involved in amino acid metabolism (AGXT2, ALDH4A1). Symbionts exhibited decreased photosystem II (PSII) activity, reactive oxygen species (ROS) accumulation, and expulsion. Notably, partial recovery was achieved under 27 ppt hypo-salinity, whereas 20 ppt induced irreversible damage. Collectively, T. crocea copes with hypo-saline stress through coordinated regulation of ion transport, amino acid metabolism, and symbiont functionality, with 27 ppt potentially emerging as a critical threshold for recoverable adaptation. These findings provide valuable mechanistic insights to inform coral reef conservation strategies under global climate change.
(Copyright © 2025 Elsevier Inc. All rights reserved.)
Contributed Indexing: Keywords: Hypo-salinity; Meta-transcriptome; Symbiosis; Tridacna crocea; Zooxanthellae
Entry Date(s): Date Created: 20250722 Date Completed: 20251017 Latest Revision: 20251017
Update Code: 20251018
DOI: 10.1016/j.envres.2025.122385
PMID: 40692024
Database: MEDLINE
Description
Abstract:Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br />Typhoon climates and extreme rainy seasons drive changes in seawater salinity and quality, threatening coral reef ecosystems. As key contributors to coral reef ecosystems, giant clams face major survival pressures from salinity fluctuations. Understanding their salinity adaptation and recovery strategies is thus critical for the long-term conservation and sustainable management of coral reefs. Here, we integrated physiological and meta-transcriptomic analyses to investigate responses of Tridacna crocea to hypo-saline conditions (20 ppt, 27 ppt) and subsequent recovery at 34 ppt. Hypo-salinity significantly reduced growth and survival, with only 69 % survival at 20 ppt, while elevated sodium-potassium pump (NKA) activity was observed, facilitating ion balance maintenance. Meta-transcriptomic analysis revealed downregulated genes related to antioxidants (GGT1), ABC transporters (ABCB11, ABCA12), and fatty acid metabolism (ACAA1), alongside upregulated genes involved in amino acid metabolism (AGXT2, ALDH4A1). Symbionts exhibited decreased photosystem II (PSII) activity, reactive oxygen species (ROS) accumulation, and expulsion. Notably, partial recovery was achieved under 27 ppt hypo-salinity, whereas 20 ppt induced irreversible damage. Collectively, T. crocea copes with hypo-saline stress through coordinated regulation of ion transport, amino acid metabolism, and symbiont functionality, with 27 ppt potentially emerging as a critical threshold for recoverable adaptation. These findings provide valuable mechanistic insights to inform coral reef conservation strategies under global climate change.<br /> (Copyright © 2025 Elsevier Inc. All rights reserved.)
ISSN:1096-0953
DOI:10.1016/j.envres.2025.122385