Immunization coverage for children with cancer in Latin America and the Caribbean can be improved through strategic coordination of existing global agendas.
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| Title: | Immunization coverage for children with cancer in Latin America and the Caribbean can be improved through strategic coordination of existing global agendas. |
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| Authors: | Homsi MR; Department of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, USA., Underwood C; Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Caniza MA; Department of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA., Davey-Rothwell MA; Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. |
| Source: | Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2025 Dec; Vol. 21 (1), pp. 2509472. Date of Electronic Publication: 2025 May 26. |
| Publication Type: | Journal Article |
| Language: | English |
| Journal Info: | Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101572652 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2164-554X (Electronic) Linking ISSN: 21645515 NLM ISO Abbreviation: Hum Vaccin Immunother Subsets: MEDLINE |
| Imprint Name(s): | Publication: 2015- : Philadelphia, PA : Taylor & Francis Original Publication: Austin, Tex. : Landes Bioscience |
| MeSH Terms: | Neoplasms*/complications , Neoplasms*/therapy , Vaccination Coverage*/statistics & numerical data , Vaccination*/statistics & numerical data, Humans ; Latin America ; Caribbean Region ; Child ; Surveys and Questionnaires ; Female ; Male ; Child, Preschool ; Health Personnel ; Infant ; Adolescent |
| Abstract: | Most cases of childhood cancer occur in low- and middle-income countries. In parallel, children with cancer are more vulnerable to infections, including vaccine-preventable infections. We distributed an electronic, self-administered survey to healthcare providers working in Latin America and the Caribbean region who deliver care to children with cancer to assess the factors that influence their decision and ability to vaccinate children with cancer. Our study found that approximately half of respondents consistently requested the patient's vaccination record before starting cancer treatment and that less than 20% estimated that ≥75% of their pediatric patients were up to date on their immunizations. Only a small fraction reported having related government policies and reporting requirements for immunizing/re-immunizing children with cancer. Respondents recognize the need to immunize children with cancer; however, national policies and monitoring tools for this population are lacking. There are global initiatives to address gaps in immunization coverage and to promote the development of policy and infrastructure to support the increasing number of children with cancer. Although they have clear and distinct goals, there are opportunities to combine efforts. Integrating immunizations into national childhood cancer treatment policies and enhancing current vaccination surveillance platforms can address gaps and support an overlooked population. |
| References: | Pediatr Blood Cancer. 2008 May;50(5):983-7. (PMID: 18240170) J Clin Oncol. 2015 Sep 20;33(27):3065-73. (PMID: 26304881) JAMA Oncol. 2017 Apr 01;3(4):524-548. (PMID: 27918777) Vaccine. 2016 Dec 20;34(52):6691-6699. (PMID: 27887796) Clin Pediatr (Phila). 2020 Jun;59(6):606-613. (PMID: 32423345) Vaccine. 2019 Jun 19;37(28):3730-3734. (PMID: 31155414) Pediatrics. 2017 Mar;139(3):. (PMID: 28167517) Pediatr Blood Cancer. 2017 Feb;64(2):315-320. (PMID: 27718310) Lancet. 2021 Aug 7;398(10299):503-521. (PMID: 34273291) J Korean Med Sci. 2012 Jan;27(1):78-83. (PMID: 22219618) Hum Vaccin Immunother. 2022 Dec 31;18(1):1-16. (PMID: 34270376) Vaccine. 2025 Jan 25;45:126578. (PMID: 39662210) Br J Haematol. 2007 Jun;137(5):457-60. (PMID: 17488489) Clin Infect Dis. 2020 Dec 3;71(9):e439-e448. (PMID: 32067048) Implement Sci. 2009 Aug 07;4:50. (PMID: 19664226) Expert Rev Hematol. 2015 Oct;8(5):627-45. (PMID: 26211675) Clin Infect Dis. 2016 Jan 15;62(2):139-47. (PMID: 26354970) Vaccine. 2024 Apr 8;42 Suppl 1:S15-S27. (PMID: 36639274) Leukemia. 2006 Oct;20(10):1717-22. (PMID: 16888619) |
| Contributed Indexing: | Keywords: Childhood cancer; Latin America and the Caribbean; global; re-immunization |
| Entry Date(s): | Date Created: 20250526 Date Completed: 20250526 Latest Revision: 20250531 |
| Update Code: | 20250531 |
| PubMed Central ID: | PMC12118396 |
| DOI: | 10.1080/21645515.2025.2509472 |
| PMID: | 40418169 |
| Database: | MEDLINE |
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Nájsť tento článok vo Web of Science | Abstract: | Most cases of childhood cancer occur in low- and middle-income countries. In parallel, children with cancer are more vulnerable to infections, including vaccine-preventable infections. We distributed an electronic, self-administered survey to healthcare providers working in Latin America and the Caribbean region who deliver care to children with cancer to assess the factors that influence their decision and ability to vaccinate children with cancer. Our study found that approximately half of respondents consistently requested the patient's vaccination record before starting cancer treatment and that less than 20% estimated that ≥75% of their pediatric patients were up to date on their immunizations. Only a small fraction reported having related government policies and reporting requirements for immunizing/re-immunizing children with cancer. Respondents recognize the need to immunize children with cancer; however, national policies and monitoring tools for this population are lacking. There are global initiatives to address gaps in immunization coverage and to promote the development of policy and infrastructure to support the increasing number of children with cancer. Although they have clear and distinct goals, there are opportunities to combine efforts. Integrating immunizations into national childhood cancer treatment policies and enhancing current vaccination surveillance platforms can address gaps and support an overlooked population. |
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| ISSN: | 2164-554X |
| DOI: | 10.1080/21645515.2025.2509472 |