Smallpox Vaccines for Monkeypox: Is Emergency Vaccination Imminent?
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| Názov: | Smallpox Vaccines for Monkeypox: Is Emergency Vaccination Imminent? |
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| Autori: | Mukareem Ali S; Dow University of Health Sciences, Karachi, Pakistan., Abbasher Hussien Mohamed Ahmed K; Faculty of Medicine, University of Khartoum, Khartoum, Sudan., Ahsan A; Foundation University, School of Health Sciences, Islamabad, Pakistan., E Mustafa Ahmed G; Faculty of Medicine, University of Khartoum, Khartoum, Sudan., Fatima I; Dow University of Health Sciences, Karachi, Pakistan., Tariq Ahmed S; Dow University of Health Sciences, Karachi, Pakistan., Niaz F; Dow University of Health Sciences, Karachi, Pakistan., Ullah I; Kabir Medical College, Gandhara University, Peshawar, Pakistan., Waris A; Kabir Medical College, Gandhara University, Peshawar, Pakistan. |
| Zdroj: | Disaster medicine and public health preparedness [Disaster Med Public Health Prep] 2025 Apr 02; Vol. 19, pp. e81. Date of Electronic Publication: 2025 Apr 02. |
| Spôsob vydávania: | Journal Article |
| Jazyk: | English |
| Informácie o časopise: | Publisher: Cambridge University Press Country of Publication: United States NLM ID: 101297401 Publication Model: Electronic Cited Medium: Internet ISSN: 1938-744X (Electronic) Linking ISSN: 19357893 NLM ISO Abbreviation: Disaster Med Public Health Prep Subsets: MEDLINE |
| Imprint Name(s): | Publication: <2013>- : New York : Cambridge University Press Original Publication: Philadelphia, PA : Lippincott Williams & Wilkins |
| Výrazy zo slovníka MeSH: | Smallpox Vaccine*/therapeutic use , Mpox, Monkeypox*/prevention & control , Mpox, Monkeypox*/epidemiology , Vaccination*/methods, Humans ; Monkeypox virus/pathogenicity ; Monkeypox virus/immunology ; Animals ; Smallpox/prevention & control |
| Abstrakt: | Monkeypox virus (MPXV) is a contagious disease that has been endemic in central and west Africa since 1970, characterized by symptoms such as fever, headache, and skin rash. While there is no approved treatment for MPXV infections, vaccination has proven effective in limiting its transmission, and previous smallpox vaccinations may also provide protection against monkeypox. However, the dependence of monkeypox on animal hosts makes eradication more complicated than with smallpox. Research should focus on assessing the safety of the vaccines, their duration of immunity, and their efficacy against the prevalent strains of monkeypox. The virus's accelerated rate of mutation poses additional challenges, as does the fact that it can be transmitted through animals, making eradication more complex than with smallpox. A comprehensive global immunization strategy is needed to address these complexities and draw on lessons learned from past eradication efforts. |
| Contributed Indexing: | Keywords: Eradication; MPXV; Monkeypox; Orthopoxvirus; Smallpox; Vaccines |
| Substance Nomenclature: | 0 (Smallpox Vaccine) |
| Entry Date(s): | Date Created: 20250402 Date Completed: 20250515 Latest Revision: 20250515 |
| Update Code: | 20250519 |
| DOI: | 10.1017/dmp.2025.66 |
| PMID: | 40171842 |
| Databáza: | MEDLINE |
Nájsť tento článok vo Web of Science | Abstrakt: | Monkeypox virus (MPXV) is a contagious disease that has been endemic in central and west Africa since 1970, characterized by symptoms such as fever, headache, and skin rash. While there is no approved treatment for MPXV infections, vaccination has proven effective in limiting its transmission, and previous smallpox vaccinations may also provide protection against monkeypox. However, the dependence of monkeypox on animal hosts makes eradication more complicated than with smallpox. Research should focus on assessing the safety of the vaccines, their duration of immunity, and their efficacy against the prevalent strains of monkeypox. The virus's accelerated rate of mutation poses additional challenges, as does the fact that it can be transmitted through animals, making eradication more complex than with smallpox. A comprehensive global immunization strategy is needed to address these complexities and draw on lessons learned from past eradication efforts. |
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| ISSN: | 1938-744X |
| DOI: | 10.1017/dmp.2025.66 |