Presentation of Benefits and Harms in Cancer Screening Guidelines for Koreans: A Systematic Review.
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| Titel: | Presentation of Benefits and Harms in Cancer Screening Guidelines for Koreans: A Systematic Review. |
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| Autoren: | Han MA; Department of Preventive Medicine, Chosun University College of Medicine, Gwangju, Korea., Lee H; Department of Preventive Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea., Kim K; Health Check-up Center, Yonsei University Wonju College of Medicine, Wonju, Korea.; Center of Evidence Based Medicine, Institute of Convergence Science, Yonsei University, Seoul, Korea., Kim SJ; Department of Internal Medicine, Chosun University College of Medicine, Gwangju, Korea., Hwang EC; Center of Evidence Based Medicine, Institute of Convergence Science, Yonsei University, Seoul, Korea.; Department of Urology, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun, Korea., Jung JH; Center of Evidence Based Medicine, Institute of Convergence Science, Yonsei University, Seoul, Korea.; Department of Urology, Yonsei University Wonju College of Medicine, Wonju, Korea. |
| Quelle: | Cancer research and treatment [Cancer Res Treat] 2025 Oct; Vol. 57 (4), pp. 923-931. Date of Electronic Publication: 2025 Mar 27. |
| Publikationsart: | Journal Article; Systematic Review |
| Sprache: | English |
| Info zur Zeitschrift: | Publisher: Korean Cancer Association Country of Publication: Korea (South) NLM ID: 101155137 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2005-9256 (Electronic) Linking ISSN: 15982998 NLM ISO Abbreviation: Cancer Res Treat Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Seoul, Korea : Korean Cancer Association, |
| MeSH-Schlagworte: | Early Detection of Cancer*/methods , Early Detection of Cancer*/standards , Early Detection of Cancer*/adverse effects , Neoplasms*/diagnosis , Neoplasms*/epidemiology , Practice Guidelines as Topic*, Humans ; Mass Screening/methods ; Mass Screening/standards ; Republic of Korea/epidemiology |
| Abstract: | Purpose: This study systematically reviewed cancer screening guidelines for the Korean population to evaluate the benefits and harms of the recommended cancer screening practices. Materials and Methods: We searched international electronic databases from inception to July 2023. Two reviewers independently conducted reference screening and data extraction. Data were extracted based on recommendations from each guideline and presentation of benefits and harms. General characteristics of the cancer screening guidelines, including cancer type, recommended screening methods, certainty of evidence, were collected. Moreover, we obtained key information on the benefits and harms of screening interventions, including the quantification of their relative and absolute effects. Results: Fifteen recommendations were identified for the use of interventions for the early detection of stomach, liver, colorectal, breast, cervical, and lung cancers in nine guidelines published between 2011 and 2015. Seven guidelines collected evidence through de novo systematic reviews. Eight guidelines presented the certainty of evidence and strength of recommendations. Benefits are presented as relative risks, and harms are presented as absolute risks. Six recommendations presented the absolute effects of both benefits and harms (comparable); eight presented them unevenly, including quantifying benefits relatively but presenting harms as absolute measures (asymmetric); and one presented neither benefits nor harms (incomplete). Conclusion: More than half of guidelines fail to present the benefits and harms of screening in a balanced manner. To enable users and beneficiaries make informed decisions based on evidence, the benefits and harms supporting recommendations should be given in a transparent and balanced manner. |
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| Grant Information: | National Research Foundation of Korea; RS-2021-NR065884 Ministry of Education; RS-2022-NR070848 Ministry of Science and ICT |
| Contributed Indexing: | Keywords: Early detection of cancer; Guideline; Mass screening; Systematic review |
| Entry Date(s): | Date Created: 20250327 Date Completed: 20251013 Latest Revision: 20251120 |
| Update Code: | 20251121 |
| PubMed Central ID: | PMC12527616 |
| DOI: | 10.4143/crt.2024.1151 |
| PMID: | 40147829 |
| Datenbank: | MEDLINE |
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Nájsť tento článok vo Web of Science | Abstract: | Purpose: This study systematically reviewed cancer screening guidelines for the Korean population to evaluate the benefits and harms of the recommended cancer screening practices.<br />Materials and Methods: We searched international electronic databases from inception to July 2023. Two reviewers independently conducted reference screening and data extraction. Data were extracted based on recommendations from each guideline and presentation of benefits and harms. General characteristics of the cancer screening guidelines, including cancer type, recommended screening methods, certainty of evidence, were collected. Moreover, we obtained key information on the benefits and harms of screening interventions, including the quantification of their relative and absolute effects.<br />Results: Fifteen recommendations were identified for the use of interventions for the early detection of stomach, liver, colorectal, breast, cervical, and lung cancers in nine guidelines published between 2011 and 2015. Seven guidelines collected evidence through de novo systematic reviews. Eight guidelines presented the certainty of evidence and strength of recommendations. Benefits are presented as relative risks, and harms are presented as absolute risks. Six recommendations presented the absolute effects of both benefits and harms (comparable); eight presented them unevenly, including quantifying benefits relatively but presenting harms as absolute measures (asymmetric); and one presented neither benefits nor harms (incomplete).<br />Conclusion: More than half of guidelines fail to present the benefits and harms of screening in a balanced manner. To enable users and beneficiaries make informed decisions based on evidence, the benefits and harms supporting recommendations should be given in a transparent and balanced manner. |
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| ISSN: | 2005-9256 |
| DOI: | 10.4143/crt.2024.1151 |