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ICRP pregnant-female mesh-type reference computational phantoms part 1: development of fetal phantoms.

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Název: ICRP pregnant-female mesh-type reference computational phantoms part 1: development of fetal phantoms.
Autoři: Shin B; Department of Nuclear Engineering, Hanyang University, Seoul, Republic of Korea.; J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States of America., Kim S; Department of Nuclear Engineering, Hanyang University, Seoul, Republic of Korea., Choi C; J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States of America., Kim H; Department of Nuclear Engineering, Hanyang University, Seoul, Republic of Korea., Yeom YS; Department of Radiation Convergence Engineering, Yonsei University, Wonju, Republic of Korea., Chung BS; Department of Anatomy, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea., Nguyen TT; Department of Nuclear Engineering and Environmental Physics, Hanoi University of Science and Technology, Hanoi, Vietnam., Moon S; Department of Nuclear Engineering, Hanyang University, Seoul, Republic of Korea., Bolch WE; J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States of America., Kim CH; Department of Nuclear Engineering, Hanyang University, Seoul, Republic of Korea.
Zdroj: Physics in medicine and biology [Phys Med Biol] 2024 Dec 12; Vol. 69 (24). Date of Electronic Publication: 2024 Dec 12.
Způsob vydávání: Journal Article
Jazyk: English
Informace o časopise: Publisher: IOP Publishing Country of Publication: England NLM ID: 0401220 Publication Model: Electronic Cited Medium: Internet ISSN: 1361-6560 (Electronic) Linking ISSN: 00319155 NLM ISO Abbreviation: Phys Med Biol Subsets: MEDLINE
Imprint Name(s): Original Publication: Bristol : IOP Publishing
Výrazy ze slovníku MeSH: Phantoms, Imaging* , Fetus*/radiation effects, Female ; Humans ; Pregnancy ; Radiation Protection/instrumentation ; Monte Carlo Method ; International Agencies ; Radiometry/instrumentation ; Reference Standards
Abstrakt: Objective . The International Commission on Radiological Protection (ICRP) decided to develop pregnant-female reference computational phantoms, including the maternal and fetal phantoms, through its 2007 general recommendations. Acknowledging the advantages of the mesh geometry, the ICRP decided to develop the pregnant-female mesh-type reference computational phantoms (MRCPs) for 8, 10, 15, 20, 25, 30, 35, and 38 week fetal ages directly in the mesh format. As part of this process, the present study developed the mesh-type fetal phantoms. Approach . The reference blood-inclusive organ masses, elemental compositions, and densities were established based on various scientific literatures. Then, the phantoms were developed in accordance with the established reference dataset while reflecting the anatomical features of the developing fetus, such as fetal-age-specific anthropometric parameters, bone ossification, and contents formation time. Main results . The phantoms were developed in the tetrahedral-mesh format and can be implemented in the general-purpose Monte Carlo codes (i.e. Geant4, PHITS, MCNP6, and EGSnrc) without the necessity of the voxelization process. To explore the dosimetric impact of the developed phantoms, photon specific absorbed fractions (SAFs) were computed for energies between 10 -2 -10 1 MeV for the fetal liver and spleen as source regions and self-irradiation and cross-irradiation to the fetal brain, lungs, and urinary bladder wall as target regions. The SAFs showed the fetal-age-dependent dose trends (i.e. SAF decreases with increasing fetal age) due to organ masses increases via fetal growth. Significance . The mesh-type fetal phantoms, as part of the ICRP pregnant-female MRCPs, will be used to calculate reference dose coefficients for fetal members of the public for both the current and future ICRP general recommendations.
(© 2024 Institute of Physics and Engineering in Medicine. All rights, including for text and data mining, AI training, and similar technologies, are reserved.)
Contributed Indexing: Keywords: ICRP mesh-type reference computational phantoms; Monte Carlo; fetus; pregnant female; tetrahedral mesh
Entry Date(s): Date Created: 20241203 Date Completed: 20241212 Latest Revision: 20241212
Update Code: 20250114
DOI: 10.1088/1361-6560/ad9a35
PMID: 39626356
Databáze: MEDLINE
Popis
Abstrakt:Objective . The International Commission on Radiological Protection (ICRP) decided to develop pregnant-female reference computational phantoms, including the maternal and fetal phantoms, through its 2007 general recommendations. Acknowledging the advantages of the mesh geometry, the ICRP decided to develop the pregnant-female mesh-type reference computational phantoms (MRCPs) for 8, 10, 15, 20, 25, 30, 35, and 38 week fetal ages directly in the mesh format. As part of this process, the present study developed the mesh-type fetal phantoms. Approach . The reference blood-inclusive organ masses, elemental compositions, and densities were established based on various scientific literatures. Then, the phantoms were developed in accordance with the established reference dataset while reflecting the anatomical features of the developing fetus, such as fetal-age-specific anthropometric parameters, bone ossification, and contents formation time. Main results . The phantoms were developed in the tetrahedral-mesh format and can be implemented in the general-purpose Monte Carlo codes (i.e. Geant4, PHITS, MCNP6, and EGSnrc) without the necessity of the voxelization process. To explore the dosimetric impact of the developed phantoms, photon specific absorbed fractions (SAFs) were computed for energies between 10 <sup>-2</sup> -10 <sup>1</sup> MeV for the fetal liver and spleen as source regions and self-irradiation and cross-irradiation to the fetal brain, lungs, and urinary bladder wall as target regions. The SAFs showed the fetal-age-dependent dose trends (i.e. SAF decreases with increasing fetal age) due to organ masses increases via fetal growth. Significance . The mesh-type fetal phantoms, as part of the ICRP pregnant-female MRCPs, will be used to calculate reference dose coefficients for fetal members of the public for both the current and future ICRP general recommendations.<br /> (© 2024 Institute of Physics and Engineering in Medicine. All rights, including for text and data mining, AI training, and similar technologies, are reserved.)
ISSN:1361-6560
DOI:10.1088/1361-6560/ad9a35