Association of Vitamin D with Haematological Inflammatory Indices in Patients with Back Pain.
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| Titel: | Association of Vitamin D with Haematological Inflammatory Indices in Patients with Back Pain. |
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| Autoren: | Ozkan Y; Department of Physical Medicine and Rehabilitation, Adnan Menderes University, Aydin, Turkiye., Alpayci M; Department of Physical Medicine and Rehabilitation, Fizyocenter Hospital, Diyarbakir, Turkiye., Delen V; Department of Physical Medicine and Rehabilitation, Harran University, Sanliurfa, Turkiye. |
| Quelle: | Journal of the College of Physicians and Surgeons--Pakistan : JCPSP [J Coll Physicians Surg Pak] 2024 Nov; Vol. 34 (11), pp. 1299-1302. |
| Publikationsart: | Journal Article |
| Sprache: | English |
| Info zur Zeitschrift: | Publisher: College of Physicians and Surgeons Pakistan Country of Publication: Pakistan NLM ID: 9606447 Publication Model: Print Cited Medium: Internet ISSN: 1681-7168 (Electronic) Linking ISSN: 1022386X NLM ISO Abbreviation: J Coll Physicians Surg Pak Subsets: MEDLINE |
| Imprint Name(s): | Original Publication: Karachi : College of Physicians and Surgeons Pakistan, |
| MeSH-Schlagworte: | Vitamin D*/blood , Low Back Pain*/blood , Vitamin D Deficiency*/blood , Vitamin D Deficiency*/complications, Humans ; Female ; Male ; Middle Aged ; Adult ; Inflammation/blood ; C-Reactive Protein/analysis ; Neutrophils ; Leukocyte Count ; Back Pain/blood ; Biomarkers/blood |
| Abstract: | Objective: To assess the relationship between vitamin D and haematological inflammatory indices (HII) in chronic low back pain (CLBP) patients. Study Design: Descriptive study. Place and Duration of the Study: Harran University Hospital, Sanliurfa, Turkiye, between September 2023 and February 2024. Methodology: A total of 100 CLBP patients were divided into three groups according to their vitamin D levels as deficiency (<20 µg/L), insufficiency (20-30 µg/L), and sufficiency (30-80 µg/L). Demographic characteristics, serum parameters, and HII were compared among the three groups. Additionally, the association between vitamin D and other parameters were investigated. Results: The three groups were similar in terms of age (p = 0.640), gender distribution (p = 0.057), body mass index (BMI, p = 0.855), C-reactive protein (CRP, p = 0.965), leucocyte count (p = 0.979), neutrophil count (p = 0.525), lymphocyte count (p = 0.246), monocyte count (p = 0.485), platelet count (p = 0.878), and HII including neutrophil-to-lymphocyte ratio (NLR, p = 0.335), monocyte-to- lymphocyte ratio (MLR, p = 0.227), platelet-to-lymphocyte ratio (PLR) (p = 0.898), neutrophil-to-lymphocyte*platelet ratio (NLPR, p = 0.543), systemic inflammatory index (SII, p = 0.300), systemic inflammatory response index (SIRI, p = 0.187), and aggregate index of systemic inflammation (AISI, p = 0.219). No significant correlation was found between vitamin D concentration and other parameters (p >0.05). Conclusion: The coexistence of vitamin D deficiency and increased HII may accompany inflammatory conditions. However, no significant association was found between vitamin D level and HII in non-inflammatory CLBP. Key Words: Inflammation, Low back pain, Neutrophil, Complete blood count, Vitamin D. |
| Substance Nomenclature: | 1406-16-2 (Vitamin D) 9007-41-4 (C-Reactive Protein) 0 (Biomarkers) |
| Entry Date(s): | Date Created: 20241104 Date Completed: 20241104 Latest Revision: 20241114 |
| Update Code: | 20250114 |
| DOI: | 10.29271/jcpsp.2024.11.1299 |
| PMID: | 39491448 |
| Datenbank: | MEDLINE |
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Nájsť tento článok vo Web of Science | Abstract: | Objective: To assess the relationship between vitamin D and haematological inflammatory indices (HII) in chronic low back pain (CLBP) patients.<br />Study Design: Descriptive study. Place and Duration of the Study: Harran University Hospital, Sanliurfa, Turkiye, between September 2023 and February 2024.<br />Methodology: A total of 100 CLBP patients were divided into three groups according to their vitamin D levels as deficiency (<20 µg/L), insufficiency (20-30 µg/L), and sufficiency (30-80 µg/L). Demographic characteristics, serum parameters, and HII were compared among the three groups. Additionally, the association between vitamin D and other parameters were investigated.<br />Results: The three groups were similar in terms of age (p = 0.640), gender distribution (p = 0.057), body mass index (BMI, p = 0.855), C-reactive protein (CRP, p = 0.965), leucocyte count (p = 0.979), neutrophil count (p = 0.525), lymphocyte count (p = 0.246), monocyte count (p = 0.485), platelet count (p = 0.878), and HII including neutrophil-to-lymphocyte ratio (NLR, p = 0.335), monocyte-to- lymphocyte ratio (MLR, p = 0.227), platelet-to-lymphocyte ratio (PLR) (p = 0.898), neutrophil-to-lymphocyte*platelet ratio (NLPR, p = 0.543), systemic inflammatory index (SII, p = 0.300), systemic inflammatory response index (SIRI, p = 0.187), and aggregate index of systemic inflammation (AISI, p = 0.219). No significant correlation was found between vitamin D concentration and other parameters (p >0.05).<br />Conclusion: The coexistence of vitamin D deficiency and increased HII may accompany inflammatory conditions. However, no significant association was found between vitamin D level and HII in non-inflammatory CLBP.<br />Key Words: Inflammation, Low back pain, Neutrophil, Complete blood count, Vitamin D. |
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| ISSN: | 1681-7168 |
| DOI: | 10.29271/jcpsp.2024.11.1299 |