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Microwave imaging for human brain stroke detection using frequency domain inverse modelling & phantom experiments.

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Název: Microwave imaging for human brain stroke detection using frequency domain inverse modelling & phantom experiments.
Autoři: Rana, Soumya Prakash1,2 (AUTHOR) soumyaprakash.rana@gmail.com, Davis, John G.1 (AUTHOR), Khalil, Kamal1 (AUTHOR), O'Toole, Michael1 (AUTHOR), Watson, Stuart3 (AUTHOR), Liang, Shijie3 (AUTHOR), Parry-Jones, Adrian4,5 (AUTHOR), Daniels, David J.1 (AUTHOR), Peyton, Anthony J.1 (AUTHOR)
Zdroj: Scientific Reports. 10/6/2025, Vol. 15 Issue 1, p1-19. 19p.
Témata: *MICROWAVE imaging, *INVERSE synthetic aperture radar, *BISTATIC radar, *CEREBRAL infarction, *DIAGNOSTIC imaging, *TESTING equipment, *BIOLOGICAL specimen analysis, *BIOLOGICAL specimens
Abstrakt: This paper reports a study exploring microwave Inverse Synthetic Aperture Radar (ISAR) imaging of biological specimens, with the longer-term goal of assessing its applicability for non-invasive and non-destructive imaging of the human brain in the context of stroke detection and monitoring. The paper describes the design and fabrication of a laboratory testbed developed to examine the feasibility of the ISAR approach. The system includes a custom antenna designed to reduce self-generated clutter and support the imaging process. Water was used as a matching medium due to its specific permittivity-frequency relationship, providing controlled conditions for experimental evaluation. The forward and inverse models were initially tested in simulated environments, and subsequently evaluated using physical measurements on real biological specimens in a bistatic radar configuration, to assess their ability to localize internal anomalies with sub-centimetre resolution across a 26 cm circular imaging area. The reconstructed images from vegetable phantoms such as potatoes and turnips suggest the technique may be capable of detecting internal structural variations. These preliminary findings serve as a foundation for future investigations into human brain imaging applications. [ABSTRACT FROM AUTHOR]
Databáze: Academic Search Index
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Abstrakt:This paper reports a study exploring microwave Inverse Synthetic Aperture Radar (ISAR) imaging of biological specimens, with the longer-term goal of assessing its applicability for non-invasive and non-destructive imaging of the human brain in the context of stroke detection and monitoring. The paper describes the design and fabrication of a laboratory testbed developed to examine the feasibility of the ISAR approach. The system includes a custom antenna designed to reduce self-generated clutter and support the imaging process. Water was used as a matching medium due to its specific permittivity-frequency relationship, providing controlled conditions for experimental evaluation. The forward and inverse models were initially tested in simulated environments, and subsequently evaluated using physical measurements on real biological specimens in a bistatic radar configuration, to assess their ability to localize internal anomalies with sub-centimetre resolution across a 26 cm circular imaging area. The reconstructed images from vegetable phantoms such as potatoes and turnips suggest the technique may be capable of detecting internal structural variations. These preliminary findings serve as a foundation for future investigations into human brain imaging applications. [ABSTRACT FROM AUTHOR]
ISSN:20452322
DOI:10.1038/s41598-025-18729-w