Bibliographic Details
| Title: |
Five new phenolics from the red resin of Dracaena cochinchinensis. |
| Authors: |
Shi, Hong1,2, Lin, Nan-Pu2, Cheng, Yong-Xian1,2 yxcheng@szu.edu.cn |
| Source: |
Journal of Asian Natural Products Research. Jul2025, Vol. 27 Issue 7, p966-976. 11p. |
| Subject Terms: |
*PHENOL analysis, *CHINESE medicine, *RESEARCH funding, *NUCLEAR magnetic resonance spectroscopy, *FLAVONOIDS, *HERBAL medicine, *FLAVONES, *FIBROSIS, *GUMS & resins, *EXPERIMENTAL design, *MEDICINAL plants, *GLYCOSIDES, *MOLECULAR structure, *MASS spectrometry, *SPECTRUM analysis, *WESTERN immunoblotting, *KIDNEY diseases |
| Abstract: |
Five undescribed phenolics including three new flavonoids (1-3), one new flavone glycoside (4) and one neolignan (5), together with seven known compounds were isolated from the resins of Dracaena cochinchinensis (Chinese dragon's blood). Their structures were elucidated based on detailed spectroscopic analysis, including 1D, 2D NMR, mass spectrometry, and electronic circular dichroism (ECD) data analysis. In addition, biological evaluation of compounds 1–5 on anti-renal fibrotic activities were conducted, and the results showed that compounds 1a, 2, and 5 display anti-renal fibrotic activities in TFG-β induced NRK-52e cells. [ABSTRACT FROM AUTHOR] |
| Database: |
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