Interleukin-14 Prevents Cytarabine or Irradiation Induced Neutropenia via JAK/STAT3 Signaling

Severe neutropenia significantly increases the risk of bacterial infections. Recent studies have shown that the cytokine interleukin 14 (IL-14) plays an important role in immune cells, but its potential role in neutropenia induced by cytarabine (ara-c) or irradiation is unclear. To investigate the r...

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Bibliographic Details
Published in:	Iranian journal of immunology Vol. 22; no. 2; p. 106
Main Authors:	Xu, Shengnan, Ye, Chaoqiong, Wu, Zhihua, Wen, Chuying, Huang, Wenhui, Deng, Cong, Hua, Jiaye, Xie, Wei, Xiao, Min
Format:	Journal Article
Language:	English
Published:	Iran Shiraz Institute for Cancer Research 23.06.2025
Subjects:	Bone marrow Chemotherapy Cytarabine Cytokines Flow cytometry Interleukin 14 Leukocytes (neutrophilic) Lymphocytes Neutropenia Neutrophils Peripheral blood Phosphorylation Radiation Serum levels Stat3 protein Western blotting Interleukin-14 Irradiation Cytarabine STAT3 Neutropenia
ISSN:	1735-1383, 1735-367X, 1735-367X
Online Access:	Get full text
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