Analysis of the changes of bacterial spectrum and drug resistance in sputum culture of ICU children in a hospital of pediatric in Jiangsu Province from 2017 to 2022

To investigate the changes of the distribution and drug resistance profile of bacteria from ICU children with lower respiratory tract infection (LRTI) in Suzhou City, Jiangsu Province from 2017 to 2022. From January 2017 to December 2022, a cross-sectional observational study on the bacterial spectr...

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Veröffentlicht in:Zhōnghuá yùfáng-yīxué zázhì Jg. 58; H. 10; S. 1534
Hauptverfasser: Huang, H, Wei, J, Shen, H J, Tan, Q X, Xue, J, Wang, C
Format: Journal Article
Sprache:Chinesisch
Veröffentlicht: China 06.10.2024
Schlagworte:
Acinetobacter baumannii - drug effects
Acinetobacter baumannii - isolation & purification
Anti-Bacterial Agents - pharmacology
Bacteria - drug effects
Bacteria - isolation & purification
Child
Child, Preschool
China
Cross-Sectional Studies
Drug Resistance, Bacterial
Female
Haemophilus influenzae - drug effects
Haemophilus influenzae - isolation & purification
Humans
Infant
Intensive Care Units
Male
Microbial Sensitivity Tests
Respiratory Tract Infections - microbiology
Sputum - microbiology
Staphylococcus aureus - drug effects
Streptococcus pneumoniae - drug effects
China
ISSN:0253-9624
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Zusammenfassung:To investigate the changes of the distribution and drug resistance profile of bacteria from ICU children with lower respiratory tract infection (LRTI) in Suzhou City, Jiangsu Province from 2017 to 2022. From January 2017 to December 2022, a cross-sectional observational study on the bacterial spectrum analysis among intensive care unit (ICU) children with LRTI was conducted in Children's Hospital of Soochow University. The bacteria was cultivated by culture methods from sputum samples, and identified by MALDI-TOF mass spectrometry. Drug sensitivity tests were performed by the VITEK2 Compact fully automated analysis system and the paper slide method. The test or Fisher's exact probability was used to analyze the changes of the distribution of sputum culture-positive bacteria and drug resistance in ICU children. The overall detection rate of sputum culture was 42.06% (1 182/2 810). (25.63%,303/1 182), (13.62%,161/1 182) and (13.28%,157/1 182) were the top three. Proportions of (17.90% 11.02%, ²=11.17, =0.001),
Bibliographie:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0253-9624
DOI:10.3760/cma.j.cn112150-20240514-00386