Tongue swabs: a novel tool for tuberculosis screening

Tuberculosis (TB) remains a significant global public health threat. Achieving the 2035 target for TB elimination requires interrupting its community transmission, which depends critically on enhancing case detection. Active screening for TB in community populations is crucial in order to address th...

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Published in:Zhonghua jiehe he huxi zazhi Vol. 48; no. 7; p. 605
Main Authors: Pang, Y, Li, L
Format: Journal Article
Language:Chinese
Published: China 12.07.2025
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ISSN:1001-0939
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Abstract Tuberculosis (TB) remains a significant global public health threat. Achieving the 2035 target for TB elimination requires interrupting its community transmission, which depends critically on enhancing case detection. Active screening for TB in community populations is crucial in order to address the current shortfall in case detection through passive, symptom-based approaches. However, obtaining sputum specimens from these populations is challenging. In recent years, various alternative specimen types to sputum have emerged for use in active case-finding strategies for TB patients. Of these, the tongue swab is the most promising new, non-invasive specimen type for TB detection. Integrating advanced methods, such as artificial intelligence-based radiological imaging, could effectively facilitate the development of an active TB case-finding strategy in the community.
AbstractList Tuberculosis (TB) remains a significant global public health threat. Achieving the 2035 target for TB elimination requires interrupting its community transmission, which depends critically on enhancing case detection. Active screening for TB in community populations is crucial in order to address the current shortfall in case detection through passive, symptom-based approaches. However, obtaining sputum specimens from these populations is challenging. In recent years, various alternative specimen types to sputum have emerged for use in active case-finding strategies for TB patients. Of these, the tongue swab is the most promising new, non-invasive specimen type for TB detection. Integrating advanced methods, such as artificial intelligence-based radiological imaging, could effectively facilitate the development of an active TB case-finding strategy in the community.
Tuberculosis (TB) remains a significant global public health threat. Achieving the 2035 target for TB elimination requires interrupting its community transmission, which depends critically on enhancing case detection. Active screening for TB in community populations is crucial in order to address the current shortfall in case detection through passive, symptom-based approaches. However, obtaining sputum specimens from these populations is challenging. In recent years, various alternative specimen types to sputum have emerged for use in active case-finding strategies for TB patients. Of these, the tongue swab is the most promising new, non-invasive specimen type for TB detection. Integrating advanced methods, such as artificial intelligence-based radiological imaging, could effectively facilitate the development of an active TB case-finding strategy in the community.Tuberculosis (TB) remains a significant global public health threat. Achieving the 2035 target for TB elimination requires interrupting its commun
Author Li, L
Pang, Y
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  organization: Department of Bacteriology and Immunology, Beijing Chest Hospital, Capital Medical University, Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China
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  givenname: L
  surname: Li
  fullname: Li, L
  organization: Beijing Chest Hospital affiliated to Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China
BackLink https://www.ncbi.nlm.nih.gov/pubmed/40582972$$D View this record in MEDLINE/PubMed
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SubjectTerms Artificial Intelligence
Humans
Mass Screening - methods
Mycobacterium tuberculosis - isolation & purification
Specimen Handling - methods
Sputum - microbiology
Tongue - microbiology
Tuberculosis - diagnosis
Title Tongue swabs: a novel tool for tuberculosis screening
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