T cell memory. Skin-resident memory CD8⁺ T cells trigger a state of tissue-wide pathogen alert

After an infection, pathogen-specific tissue-resident memory T cells (T(RM) cells) persist in nonlymphoid tissues to provide rapid control upon reinfection, and vaccination strategies that create T(RM) cell pools at sites of pathogen entry are therefore attractive. However, it is not well understood...

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Vydané v:	Science (American Association for the Advancement of Science) Ročník 346; číslo 6205; s. 101
Hlavní autori:	Ariotti, Silvia, Hogenbirk, Marc A, Dijkgraaf, Feline E, Visser, Lindy L, Hoekstra, Mirjam E, Song, Ji-Ying, Jacobs, Heinz, Haanen, John B, Schumacher, Ton N
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 03.10.2014
Predmet:	Animals CD8-Positive T-Lymphocytes - immunology Female Immunologic Memory - genetics Immunologic Memory - immunology Male Mice Skin - immunology Skin - microbiology Skin - virology Transcriptome
ISSN:	1095-9203, 1095-9203
On-line prístup:	Zistit podrobnosti o prístupe
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