Direct effects of polymyxin B on human dendritic cells maturation. The role of IkappaB-alpha/NF-kappaB and ERK1/2 pathways and adhesion

Polymyxin B is a lipopolysaccharide binding antibiotic used to inactivate potential lipopolysaccharide contaminations when evaluating the activity of different agents on innate immune cells. We report that polymyxin B is able to induce directly in monocyte-derived human dendritic cells (DCs) several...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	The Journal of biological chemistry Ročník 280; číslo 14; s. 14264
Hlavní autori:	Valentinis, Barbara, Bianchi, Alessandro, Zhou, Dan, Cipponi, Arcadi, Catalanotti, Federica, Russo, Vincenzo, Traversari, Catia
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 08.04.2005
Predmet:	Anti-Bacterial Agents - pharmacology Antigens, CD - genetics Antigens, CD - metabolism B7-2 Antigen Cell Adhesion - drug effects Cell Adhesion - physiology Cells, Cultured Cytokines - metabolism Dendritic Cells - cytology Dendritic Cells - drug effects Dendritic Cells - immunology Dendritic Cells - physiology Enzyme Activation Enzyme Inhibitors - metabolism Extracellular Signal-Regulated MAP Kinases - metabolism Flavonoids - metabolism Genes, MHC Class I Genes, MHC Class II HLA Antigens - genetics HLA Antigens - metabolism Humans I-kappa B Proteins - metabolism Membrane Glycoproteins - genetics Membrane Glycoproteins - metabolism NF-kappa B - metabolism NF-KappaB Inhibitor alpha p38 Mitogen-Activated Protein Kinases - metabolism Polymyxin B - pharmacology Signal Transduction - physiology Tosylphenylalanyl Chloromethyl Ketone - metabolism
ISSN:	0021-9258
On-line prístup:	Zistit podrobnosti o prístupe
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!