Pancreatic kallikrein, a protector of small intestine damage in post-ischemic toxemia

The morphofunctional state of the small intestine was studied on a tourniquet shock model. The development of postischemic toxemia is followed by disorders of microcirculation leading to irreversible changes in the small intestine. The processes are associated with an increase of the proteolytic act...

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Bibliographic Details
Published in:	Farmakologiia i toksikologiia Vol. 52; no. 4; p. 34
Main Authors:	Protsenko, V A, Lutsik, N G, Nesterov, E N, Kharchenko, V Z
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01.07.1989
Subjects:	Animals Drug Combinations - therapeutic use Intestine, Small - blood supply Ischemia - complications Ischemia - prevention & control Kallikreins - therapeutic use Microcirculation - drug effects Pancreas - enzymology Pancreatic Extracts - therapeutic use Povidone - therapeutic use Rats Rats, Inbred Strains Toxemia - drug therapy Toxemia - etiology
ISSN:	0014-8318
Online Access:	Get more information
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Summary:	The morphofunctional state of the small intestine was studied on a tourniquet shock model. The development of postischemic toxemia is followed by disorders of microcirculation leading to irreversible changes in the small intestine. The processes are associated with an increase of the proteolytic activity of the intestinal contents. An oral administration of andecaline prevents ischemia of the intestine, contributes to the preservation of its mucosa.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0014-8318