APOE ε4 carrier status moderates the effect of lifestyle factors on cognitive reserve

INTRODUCTION This study examines the role of lifestyle factors in cognitive reserve among older adults, focusing on the moderating effect of apolipoprotein E (APOE) ε4 status. METHODS Data from 157 participants aged 45 and older from the Healthy Brain Initiative (HBI) were analyzed. Cognitive reserv...

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Bibliographic Details
Published in:	Alzheimer's & dementia Vol. 20; no. 11; pp. 8062 - 8073
Main Authors:	O'Shea, Deirdre M., Zhang, Andrea S., Rader, Katana, Shakour, Rebecca L., Besser, Lilah, Galvin, James E.
Format:	Journal Article
Language:	English
Published:	United States John Wiley and Sons Inc 01.11.2024
Subjects:	Aged Alzheimer's disease APOE ε4 status Apolipoprotein E4 - genetics Brain cognitive function cognitive reserve Cognitive Reserve - physiology Female Heterozygote Humans Life Style lifestyle factors Magnetic Resonance Imaging Male Middle Aged Mindfulness Neuropsychological Tests - statistics & numerical data APOE ε4 status cognitive function lifestyle factors Alzheimer's disease cognitive reserve
ISSN:	1552-5260, 1552-5279, 1552-5279
Online Access:	Get full text
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