The effect of preoperative smoking and smoke cessation on wound healing and infection in post‐surgery subjects: A meta‐analysis

A meta‐analysis was performed to evaluate the preoperative smoking and smoke cessation on wound healing and infection in post‐surgery subjects. A systematic literature search up to January 2022 incorporated 11 trials involving 218 567 subjects after post‐surgery at the beginning of the study; 176 67...

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Vydáno v:International wound journal Ročník 19; číslo 8; s. 2101 - 2106
Hlavní autoři: Liu, Dazhen, Zhu, Long, Yang, Changhai
Médium: Journal Article
Jazyk:angličtina
Vydáno: Oxford, UK Blackwell Publishing Ltd 01.12.2022
John Wiley & Sons, Inc
Témata:
Abstinence
Bias
Collaboration
Humans
Infections
Intervention
Meta-analysis
non‐smoker
Odds Ratio
Original
postoperative wound healing problems
post‐surgery
Sensitivity analysis
smoke cessation
Smoking - adverse effects
Smoking Cessation - methods
Statistical analysis
Surgery
surgical site wound infection
Surgical Wound Infection
Wound Healing
Denmark
United States > US
Sweden
surgical site wound infection
post-surgery
postoperative wound healing problems
non-smoker
smoke cessation
ISSN:1742-4801, 1742-481X, 1742-481X
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Shrnutí:A meta‐analysis was performed to evaluate the preoperative smoking and smoke cessation on wound healing and infection in post‐surgery subjects. A systematic literature search up to January 2022 incorporated 11 trials involving 218 567 subjects after post‐surgery at the beginning of the study; 176 670 were smoke cessation or non‐smokers, and 41 897 were smokers. Statistical tools like the dichotomous method were used within a random or fixed‐influence model to establish the odds ratio (OR) with 95% confidence intervals (CIs) to evaluate the influence of preoperative smoking and smoke cessation on wound healing and infection in post‐surgery subjects. Smoke cessation or non‐smokers had significantly lower postoperative wound healing problems (OR, 0.59; 95% confidence interval, 0.43‐0.82, P < .001), and surgical site wound infection (OR, 0.74; 95% CI, 0.63‐0.87, P < .001) compared with smokers in post‐surgery subjects. Smoke cessation or non‐smokers had significantly lower postoperative wound healing problems, and surgical site wound infection compared with smokers in post‐surgery subjects. Furthermore, evidence is needed to confirm the outcomes.
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ISSN:1742-4801
1742-481X
1742-481X
DOI:10.1111/iwj.13815