Antigen-presenting capacity of rheumatoid synovial fibroblasts

In normal, healthy joints, synovial fibroblasts do not express major histocompatibility complex (MHC) class II molecules. However, in inflamed joints of rheumatoid arthritis (RA) patients, synovial fibroblasts show an abundant expression of MHC class II. Does this increase in expression have functio...

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Bibliographic Details

Published in:	Immunology Vol. 82; no. 2; p. 268
Main Authors:	Boots, A M, Wimmers-Bertens, A J, Rijnders, A W
Format:	Journal Article
Language:	English
Published:	England 01.06.1994
Subjects:	Antigen-Presenting Cells - immunology Antigens, Bacterial - immunology Antigens, Surface - analysis Arthritis, Rheumatoid - immunology Cell Line Cells, Cultured Dose-Response Relationship, Immunologic Fibroblasts - immunology HLA-DR Antigens - analysis Humans Interferon-gamma - immunology Recombinant Proteins Synovial Membrane - immunology Tetanus Toxoid - immunology
ISSN:	0019-2805
Online Access:	Get more information
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